Kawagoe F - Search Results

1

Concise synthesis of 23-hydroxylated vitamin D₃ metabolites.

Kawagoe F, Sugiyama T, Yasuda K, Uesugi M, Sakaki T, Kittaka A. Kawagoe F, et al. J Steroid Biochem Mol Biol. 2019 Feb;186:161-168. doi: 10.1016/j.jsbmb.2018.10.010. Epub 2018 Oct 24. J Steroid Biochem Mol Biol. 2019. PMID: 30367940

2

Synthesis of 2α- and 2β-(3-hydroxypropyl)- 7,8-cis-14-epi-1α,25-dihydroxy-19-norvitamin D₃ and their biological activity.

Sawada D, Ochiai E, Takeuchi A, Kakuda S, Kamimura-Takimoto M, Kawagoe F, Kittaka A. Sawada D, et al. Among authors: kawagoe f. J Steroid Biochem Mol Biol. 2017 Oct;173:79-82. doi: 10.1016/j.jsbmb.2016.09.007. Epub 2016 Sep 11. J Steroid Biochem Mol Biol. 2017. PMID: 27629592

3

Recent developments for introducing a hexafluoroisopropanol unit into the Vitamin D side chain.

Kawagoe F, Sugiyama T, Uesugi M, Kittaka A. Kawagoe F, et al. J Steroid Biochem Mol Biol. 2018 Mar;177:250-254. doi: 10.1016/j.jsbmb.2017.07.008. Epub 2017 Jul 14. J Steroid Biochem Mol Biol. 2018. PMID: 28716761 Review.

4

Effects of 2-substitution on 14-epi-19-nortachysterol-mediated biological events: based on synthesis and X-ray co-crystallographic analysis with the human vitamin D receptor.

Sawada D, Kakuda S, Takeuchi A, Kawagoe F, Takimoto-Kamimura M, Kittaka A. Sawada D, et al. Among authors: kawagoe f. Org Biomol Chem. 2018 Apr 4;16(14):2448-2455. doi: 10.1039/C8OB00158H. Org Biomol Chem. 2018. PMID: 29560490

5

Synthesis and CYP24A1-Dependent Metabolism of 23-Fluorinated Vitamin D₃ Analogues.

Kawagoe F, Yasuda K, Mototani S, Sugiyama T, Uesugi M, Sakaki T, Kittaka A. Kawagoe F, et al. ACS Omega. 2019 Jun 28;4(6):11332-11337. doi: 10.1021/acsomega.9b01500. eCollection 2019 Jun 30. ACS Omega. 2019. PMID: 31460236 Free PMC article.

6

Introduction of fluorine atoms to vitamin D₃ side-chain and synthesis of 24,24-difluoro-25-hydroxyvitamin D₃.

Kawagoe F, Mototani S, Yasuda K, Nagasawa K, Uesugi M, Sakaki T, Kittaka A. Kawagoe F, et al. J Steroid Biochem Mol Biol. 2019 Dec;195:105477. doi: 10.1016/j.jsbmb.2019.105477. Epub 2019 Sep 18. J Steroid Biochem Mol Biol. 2019. PMID: 31541729

7

Synthetic Chemical Probes That Dissect Vitamin D Activities.

Nagata A, Akagi Y, Asano L, Kotake K, Kawagoe F, Mendoza A, Masoud SS, Usuda K, Yasui K, Takemoto Y, Kittaka A, Nagasawa K, Uesugi M. Nagata A, et al. Among authors: kawagoe f. ACS Chem Biol. 2019 Dec 20;14(12):2851-2858. doi: 10.1021/acschembio.9b00718. Epub 2019 Oct 28. ACS Chem Biol. 2019. PMID: 31618573 Free article.

8

Elucidation of metabolic pathways of 25-hydroxyvitamin D3 mediated by CYP24A1 and CYP3A using Cyp24a1 knockout rats generated by CRISPR/Cas9 system.

Yasuda K, Nishikawa M, Okamoto K, Horibe K, Mano H, Yamaguchi M, Okon R, Nakagawa K, Tsugawa N, Okano T, Kawagoe F, Kittaka A, Ikushiro S, Sakaki T. Yasuda K, et al. Among authors: kawagoe f. J Biol Chem. 2021 Jan-Jun;296:100668. doi: 10.1016/j.jbc.2021.100668. Epub 2021 Apr 15. J Biol Chem. 2021. PMID: 33865853 Free PMC article.

9

Discovery of a Vitamin D Receptor-Silent Vitamin D Derivative That Impairs Sterol Regulatory Element-Binding Protein In Vivo.

Kawagoe F, Mendoza A, Hayata Y, Asano L, Kotake K, Mototani S, Kawamura S, Kurosaki S, Akagi Y, Takemoto Y, Nagasawa K, Nakagawa H, Uesugi M, Kittaka A. Kawagoe F, et al. J Med Chem. 2021 May 13;64(9):5689-5709. doi: 10.1021/acs.jmedchem.0c02179. Epub 2021 Apr 24. J Med Chem. 2021. PMID: 33899473

10

Design and Synthesis of Fluoro Analogues of Vitamin D.

Kawagoe F, Mototani S, Kittaka A. Kawagoe F, et al. Int J Mol Sci. 2021 Jul 30;22(15):8191. doi: 10.3390/ijms22158191. Int J Mol Sci. 2021. PMID: 34360956 Free PMC article. Review.

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