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Page 1
Refining the structure-activity relationships of 2-phenylcyclopropane carboxylic acids as inhibitors of O-acetylserine sulfhydrylase isoforms.
Magalhães J, Franko N, Annunziato G, Pieroni M, Benoni R, Nikitjuka A, Mozzarelli A, Bettati S, Karawajczyk A, Jirgensons A, Campanini B, Costantino G. Magalhães J, et al. Among authors: franko n. J Enzyme Inhib Med Chem. 2019 Dec;34(1):31-43. doi: 10.1080/14756366.2018.1518959. J Enzyme Inhib Med Chem. 2019. PMID: 30362368 Free PMC article.
Cyclopropane-1,2-dicarboxylic acids as new tools for the biophysical investigation of O-acetylserine sulfhydrylases by fluorimetric methods and saturation transfer difference (STD) NMR.
Annunziato G, Pieroni M, Benoni R, Campanini B, Pertinhez TA, Pecchini C, Bruno A, Magalhães J, Bettati S, Franko N, Mozzarelli A, Costantino G. Annunziato G, et al. Among authors: franko n. J Enzyme Inhib Med Chem. 2016;31(sup4):78-87. doi: 10.1080/14756366.2016.1218486. Epub 2016 Aug 31. J Enzyme Inhib Med Chem. 2016. PMID: 27578398
Discovery of novel fragments inhibiting O-acetylserine sulphhydrylase by combining scaffold hopping and ligand-based drug design.
Magalhães J, Franko N, Annunziato G, Welch M, Dolan SK, Bruno A, Mozzarelli A, Armao S, Jirgensons A, Pieroni M, Costantino G, Campanini B. Magalhães J, et al. Among authors: franko n. J Enzyme Inhib Med Chem. 2018 Dec;33(1):1444-1452. doi: 10.1080/14756366.2018.1512596. J Enzyme Inhib Med Chem. 2018. PMID: 30221554 Free PMC article.
Investigational Studies on a Hit Compound Cyclopropane-Carboxylic Acid Derivative Targeting O-Acetylserine Sulfhydrylase as a Colistin Adjuvant.
Annunziato G, Spadini C, Franko N, Storici P, Demitri N, Pieroni M, Flisi S, Rosati L, Iannarelli M, Marchetti M, Magalhaes J, Bettati S, Mozzarelli A, Cabassi CS, Campanini B, Costantino G. Annunziato G, et al. Among authors: franko n. ACS Infect Dis. 2021 Feb 12;7(2):281-292. doi: 10.1021/acsinfecdis.0c00378. Epub 2021 Jan 29. ACS Infect Dis. 2021. PMID: 33513010
Discovery of Substituted (2-Aminooxazol-4-yl)Isoxazole-3-carboxylic Acids as Inhibitors of Bacterial Serine Acetyltransferase in the Quest for Novel Potential Antibacterial Adjuvants.
Magalhães J, Franko N, Raboni S, Annunziato G, Tammela P, Bruno A, Bettati S, Armao S, Spadini C, Cabassi CS, Mozzarelli A, Pieroni M, Campanini B, Costantino G. Magalhães J, et al. Among authors: franko n. Pharmaceuticals (Basel). 2021 Feb 23;14(2):174. doi: 10.3390/ph14020174. Pharmaceuticals (Basel). 2021. PMID: 33672408 Free PMC article.
Inhibitors of O-Acetylserine Sulfhydrylase with a Cyclopropane-Carboxylic Acid Scaffold Are Effective Colistin Adjuvants in Gram Negative Bacteria.
Annunziato G, Spadini C, Marchetti M, Franko N, Pavone M, Iannarelli M, Bruno A, Pieroni M, Bettati S, Cabassi CS, Campanini B, Costantino G. Annunziato G, et al. Among authors: franko n. Pharmaceuticals (Basel). 2022 Jun 20;15(6):766. doi: 10.3390/ph15060766. Pharmaceuticals (Basel). 2022. PMID: 35745685 Free PMC article.
Combination of SAXS and Protein Painting Discloses the Three-Dimensional Organization of the Bacterial Cysteine Synthase Complex, a Potential Target for Enhancers of Antibiotic Action.
Rosa B, Marchetti M, Paredi G, Amenitsch H, Franko N, Benoni R, Giabbai B, De Marino MG, Mozzarelli A, Ronda L, Storici P, Campanini B, Bettati S. Rosa B, et al. Among authors: franko n. Int J Mol Sci. 2019 Oct 21;20(20):5219. doi: 10.3390/ijms20205219. Int J Mol Sci. 2019. PMID: 31640223 Free PMC article.
54 results