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The minor gentamicin complex component, X2, is a potent premature stop codon readthrough molecule with therapeutic potential.
PLoS One. 2018 Oct 25;13(10):e0206158. doi: 10.1371/journal.pone.0206158. eCollection 2018.
PLoS One. 2018.
PMID: 30359426
Free PMC article.
Guanidino quinazolines and pyrimidines promote readthrough of premature termination codons in cells with native nonsense mutations.
Morrill C, Friesen WJ, Babu S, Baiazitov RY, Du W, Karloff DB, Lee CS, Moon YC, Ren H, Sierra J, Tomizawa Y, Vazirani P, Welch EM, Xue X, Zhuo J.
Morrill C, et al. Among authors: vazirani p.
Bioorg Med Chem Lett. 2022 Nov 15;76:128989. doi: 10.1016/j.bmcl.2022.128989. Epub 2022 Sep 20.
Bioorg Med Chem Lett. 2022.
PMID: 36150638
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Motor neuron disease. SMN2 splicing modifiers improve motor function and longevity in mice with spinal muscular atrophy.
Naryshkin NA, Weetall M, Dakka A, Narasimhan J, Zhao X, Feng Z, Ling KK, Karp GM, Qi H, Woll MG, Chen G, Zhang N, Gabbeta V, Vazirani P, Bhattacharyya A, Furia B, Risher N, Sheedy J, Kong R, Ma J, Turpoff A, Lee CS, Zhang X, Moon YC, Trifillis P, Welch EM, Colacino JM, Babiak J, Almstead NG, Peltz SW, Eng LA, Chen KS, Mull JL, Lynes MS, Rubin LL, Fontoura P, Santarelli L, Haehnke D, McCarthy KD, Schmucki R, Ebeling M, Sivaramakrishnan M, Ko CP, Paushkin SV, Ratni H, Gerlach I, Ghosh A, Metzger F.
Naryshkin NA, et al. Among authors: vazirani p.
Science. 2014 Aug 8;345(6197):688-93. doi: 10.1126/science.1250127.
Science. 2014.
PMID: 25104390
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Specific Correction of Alternative Survival Motor Neuron 2 Splicing by Small Molecules: Discovery of a Potential Novel Medicine To Treat Spinal Muscular Atrophy.
Ratni H, Karp GM, Weetall M, Naryshkin NA, Paushkin SV, Chen KS, McCarthy KD, Qi H, Turpoff A, Woll MG, Zhang X, Zhang N, Yang T, Dakka A, Vazirani P, Zhao X, Pinard E, Green L, David-Pierson P, Tuerck D, Poirier A, Muster W, Kirchner S, Mueller L, Gerlach I, Metzger F.
Ratni H, et al. Among authors: vazirani p.
J Med Chem. 2016 Jul 14;59(13):6086-100. doi: 10.1021/acs.jmedchem.6b00459. Epub 2016 Jul 6.
J Med Chem. 2016.
PMID: 27299419
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To Evaluate the 'Real World' Clinical Performance of Bisoprolol in Post-Myocardial Infarction with Left Ventricular Dysfunction: Tenacity Study.
Sharma K, Desai H, Sharm N, Laddha M, Hansora K, Vazirani P.
Sharma K, et al. Among authors: vazirani p.
J Assoc Physicians India. 2022 Apr;70(4):11-12.
J Assoc Physicians India. 2022.
PMID: 35443400
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Asymmetric septal hypertrophy associated with hypothyroidism.
Vazirani P, Sharma J, Gandhi V, Dave S.
Vazirani P, et al.
Indian Pediatr. 1990 Jan;27(1):76-8.
Indian Pediatr. 1990.
PMID: 2361745
No abstract available.
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Electroversion in treatment of arrhythmias following acute myocardial infarction.
Vazirani PH, Tolia MH, Chatterji JC.
Vazirani PH, et al.
Indian Heart J. 1980 May-Jun;32(3):137-40.
Indian Heart J. 1980.
PMID: 7409842
No abstract available.
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