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Anticarin-β shows a promising anti-osteosarcoma effect by specifically inhibiting CCT4 to impair proteostasis.
Wang G, Zhang M, Meng P, Long C, Luo X, Yang X, Wang Y, Zhang Z, Mwangi J, Kamau PM, Dai Z, Ke Z, Zhang Y, Chen W, Zhao X, Ge F, Lv Q, Rong M, Li D, Jin Y, Sheng X, Lai R. Wang G, et al. Among authors: jin y. Acta Pharm Sin B. 2022 May;12(5):2268-2279. doi: 10.1016/j.apsb.2021.12.024. Epub 2022 Jan 4. Acta Pharm Sin B. 2022. PMID: 35646538 Free PMC article.
Regulation of the unfolded protein response through ATF4 and FAM129A in prostate cancer.
Pällmann N, Livgård M, Tesikova M, Zeynep Nenseth H, Akkus E, Sikkeland J, Jin Y, Koc D, Kuzu OF, Pradhan M, Danielsen HE, Kahraman N, Mokhlis HM, Ozpolat B, Banerjee PP, Uren A, Fazli L, Rennie PS, Jin Y, Saatcioglu F. Pällmann N, et al. Among authors: jin y. Oncogene. 2019 Aug;38(35):6301-6318. doi: 10.1038/s41388-019-0879-2. Epub 2019 Jul 16. Oncogene. 2019. PMID: 31312022
Molecular circuit involving KLK4 integrates androgen and mTOR signaling in prostate cancer.
Jin Y, Qu S, Tesikova M, Wang L, Kristian A, Mælandsmo GM, Kong H, Zhang T, Jerónimo C, Teixeira MR, Yuca E, Tekedereli I, Gorgulu K, Alpay N, Sood AK, Lopez-Berestein G, Danielsen HE, Ozpolat B, Saatcioglu F. Jin Y, et al. Proc Natl Acad Sci U S A. 2013 Jul 9;110(28):E2572-81. doi: 10.1073/pnas.1304318110. Epub 2013 Jun 24. Proc Natl Acad Sci U S A. 2013. PMID: 23798432 Free PMC article.
IRE1α-XBP1s pathway promotes prostate cancer by activating c-MYC signaling.
Sheng X, Nenseth HZ, Qu S, Kuzu OF, Frahnow T, Simon L, Greene S, Zeng Q, Fazli L, Rennie PS, Mills IG, Danielsen H, Theis F, Patterson JB, Jin Y, Saatcioglu F. Sheng X, et al. Among authors: jin y. Nat Commun. 2019 Jan 24;10(1):323. doi: 10.1038/s41467-018-08152-3. Nat Commun. 2019. PMID: 30679434 Free PMC article.
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