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Evolutionarily conserved Tbx5-Wnt2/2b pathway orchestrates cardiopulmonary development.
Steimle JD, Rankin SA, Slagle CE, Bekeny J, Rydeen AB, Chan SS, Kweon J, Yang XH, Ikegami K, Nadadur RD, Rowton M, Hoffmann AD, Lazarevic S, Thomas W, Boyle Anderson EAT, Horb ME, Luna-Zurita L, Ho RK, Kyba M, Jensen B, Zorn AM, Conlon FL, Moskowitz IP. Steimle JD, et al. Among authors: rowton m. Proc Natl Acad Sci U S A. 2018 Nov 6;115(45):E10615-E10624. doi: 10.1073/pnas.1811624115. Epub 2018 Oct 23. Proc Natl Acad Sci U S A. 2018. PMID: 30352852 Free PMC article.
Many ways to break a heart.
Rowton M, Moskowitz IP. Rowton M, et al. Elife. 2015 Aug 25;4:e10040. doi: 10.7554/eLife.10040. Elife. 2015. PMID: 26305497 Free PMC article.
Hedgehog-FGF signaling axis patterns anterior mesoderm during gastrulation.
Guzzetta A, Koska M, Rowton M, Sullivan KR, Jacobs-Li J, Kweon J, Hidalgo H, Eckart H, Hoffmann AD, Back R, Lozano S, Moon AM, Basu A, Bressan M, Pott S, Moskowitz IP. Guzzetta A, et al. Among authors: rowton m. Proc Natl Acad Sci U S A. 2020 Jul 7;117(27):15712-15723. doi: 10.1073/pnas.1914167117. Epub 2020 Jun 19. Proc Natl Acad Sci U S A. 2020. PMID: 32561646 Free PMC article.
Hedgehog signaling activates a mammalian heterochronic gene regulatory network controlling differentiation timing across lineages.
Rowton M, Perez-Cervantes C, Hur S, Jacobs-Li J, Lu E, Deng N, Guzzetta A, Hoffmann AD, Stocker M, Steimle JD, Lazarevic S, Oubaha S, Yang XH, Kim C, Yu S, Eckart H, Koska M, Hanson E, Chan SSK, Garry DJ, Kyba M, Basu A, Ikegami K, Pott S, Moskowitz IP. Rowton M, et al. Dev Cell. 2022 Sep 26;57(18):2181-2203.e9. doi: 10.1016/j.devcel.2022.08.009. Epub 2022 Sep 14. Dev Cell. 2022. PMID: 36108627 Free PMC article.
ETV2 primes hematoendothelial gene enhancers prior to hematoendothelial fate commitment.
Steimle JD, Kim C, Rowton M, Nadadur RD, Wang Z, Stocker M, Hoffmann AD, Hanson E, Kweon J, Sinha T, Choi K, Black BL, Cunningham JM, Moskowitz IP, Ikegami K. Steimle JD, et al. Among authors: rowton m. Cell Rep. 2023 Jun 27;42(6):112665. doi: 10.1016/j.celrep.2023.112665. Epub 2023 Jun 17. Cell Rep. 2023. PMID: 37330911 Free PMC article.