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Targeting Processive Transcription Elongation via SEC Disruption for MYC-Induced Cancer Therapy.
Cell. 2018 Oct 18;175(3):766-779.e17. doi: 10.1016/j.cell.2018.09.027.
Cell. 2018.
PMID: 30340042
Free PMC article.
Regulation of MLL/COMPASS stability through its proteolytic cleavage by taspase1 as a possible approach for clinical therapy of leukemia.
Zhao Z, Wang L, Volk AG, Birch NW, Stoltz KL, Bartom ET, Marshall SA, Rendleman EJ, Nestler CM, Shilati J, Schiltz GE, Crispino JD, Shilatifard A.
Zhao Z, et al. Among authors: stoltz kl.
Genes Dev. 2019 Jan 1;33(1-2):61-74. doi: 10.1101/gad.319830.118. Epub 2018 Dec 20.
Genes Dev. 2019.
PMID: 30573454
Free PMC article.
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7-Methylation of Chenodeoxycholic Acid Derivatives Yields a Substantial Increase in TGR5 Receptor Potency.
Nakhi A, McDermott CM, Stoltz KL, John K, Hawkinson JE, Ambrose EA, Khoruts A, Sadowsky MJ, Dosa PI.
Nakhi A, et al. Among authors: stoltz kl.
J Med Chem. 2019 Jul 25;62(14):6824-6830. doi: 10.1021/acs.jmedchem.9b00770. Epub 2019 Jul 3.
J Med Chem. 2019.
PMID: 31268316
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Effect of Cromakalim Prodrug 1 (CKLP1) on Aqueous Humor Dynamics and Feasibility of Combination Therapy With Existing Ocular Hypotensive Agents.
Roy Chowdhury U, Rinkoski TA, Bahler CK, Millar JC, Bertrand JA, Holman BH, Sherwood JM, Overby DR, Stoltz KL, Dosa PI, Fautsch MP.
Roy Chowdhury U, et al. Among authors: stoltz kl.
Invest Ophthalmol Vis Sci. 2017 Nov 1;58(13):5731-5742. doi: 10.1167/iovs.17-22538.
Invest Ophthalmol Vis Sci. 2017.
PMID: 29114841
Free PMC article.
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Synthesis and Biological Evaluation of Bile Acid Analogues Inhibitory to Clostridium difficile Spore Germination.
Stoltz KL, Erickson R, Staley C, Weingarden AR, Romens E, Steer CJ, Khoruts A, Sadowsky MJ, Dosa PI.
Stoltz KL, et al.
J Med Chem. 2017 Apr 27;60(8):3451-3471. doi: 10.1021/acs.jmedchem.7b00295. Epub 2017 Apr 12.
J Med Chem. 2017.
PMID: 28402634
Free PMC article.
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Analogs of the ATP-Sensitive Potassium (KATP) Channel Opener Cromakalim with in Vivo Ocular Hypotensive Activity.
Roy Chowdhury U, Viker KB, Stoltz KL, Holman BH, Fautsch MP, Dosa PI.
Roy Chowdhury U, et al. Among authors: stoltz kl.
J Med Chem. 2016 Jul 14;59(13):6221-31. doi: 10.1021/acs.jmedchem.6b00406. Epub 2016 Jul 1.
J Med Chem. 2016.
PMID: 27367033
Free PMC article.
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