Purine nucleoside phosphorylase: inhibition by purine N(7)- and N(9)-acyclonucleosides; and substrate properties of 7-beta-D-ribofuranosylguanine and 7-beta-D-ribofuranosylhypoxanthine.
Bzowska A, Ananiev AV, Ramzaeva N, Alksins E, Maurins JA, Kulikowska E, Shugar D.
Bzowska A, et al.
Biochem Pharmacol. 1994 Aug 30;48(5):937-47. doi: 10.1016/0006-2952(94)90364-6.
Biochem Pharmacol. 1994.
PMID: 8093106
A series of 10 N(7)- and N(9)-acyclonucleosides of guanine and 8-substituted guanines (8-Br, 8-SH and 8-NH2), and two N(7)-acyclonucleosides of hypoxanthine, were tested for their ability to inhibit purine nucleoside phosphorylase (PNP) (E.C. 2.4.2.1) from human erythrocyt …
A series of 10 N(7)- and N(9)-acyclonucleosides of guanine and 8-substituted guanines (8-Br, 8-SH and 8-NH2), and two N(7)-acyclonucl …