Handford PA - Search Results

1

Somatic mutant clones colonize the human esophagus with age.

Martincorena I, Fowler JC, Wabik A, Lawson ARJ, Abascal F, Hall MWJ, Cagan A, Murai K, Mahbubani K, Stratton MR, Fitzgerald RC, Handford PA, Campbell PJ, Saeb-Parsy K, Jones PH. Martincorena I, et al. Among authors: handford pa. Science. 2018 Nov 23;362(6417):911-917. doi: 10.1126/science.aau3879. Epub 2018 Oct 18. Science. 2018. PMID: 30337457 Free PMC article.

2

(1)H, (13)C and (15)N assignments of EGF domains 8-11 of human Notch-1.

Weisshuhn PC, Handford PA, Redfield C. Weisshuhn PC, et al. Among authors: handford pa. Biomol NMR Assign. 2015 Oct;9(2):375-9. doi: 10.1007/s12104-015-9613-3. Epub 2015 May 1. Biomol NMR Assign. 2015. PMID: 25930016

3

(1)H, (13)C and (15)N assignments of EGF domains 4 to 7 of human Notch-1.

Weisshuhn PC, Handford PA, Redfield C. Weisshuhn PC, et al. Among authors: handford pa. Biomol NMR Assign. 2015 Oct;9(2):275-9. doi: 10.1007/s12104-014-9591-x. Epub 2014 Dec 13. Biomol NMR Assign. 2015. PMID: 25503468

4

Localization of the delta-like-1-binding site in human Notch-1 and its modulation by calcium affinity.

Cordle J, Redfieldz C, Stacey M, van der Merwe PA, Willis AC, Champion BR, Hambleton S, Handford PA. Cordle J, et al. Among authors: handford pa. J Biol Chem. 2008 Apr 25;283(17):11785-93. doi: 10.1074/jbc.M708424200. Epub 2008 Feb 22. J Biol Chem. 2008. PMID: 18296446 Free article.

5

Biophysical characterisation of fibulin-5 proteins associated with disease.

Schneider R, Jensen SA, Whiteman P, McCullagh JS, Redfield C, Handford PA. Schneider R, et al. Among authors: handford pa. J Mol Biol. 2010 Aug 27;401(4):605-17. doi: 10.1016/j.jmb.2010.06.039. Epub 2010 Jun 25. J Mol Biol. 2010. PMID: 20599547

6

Molecular basis for Jagged-1/Serrate ligand recognition by the Notch receptor.

Whiteman P, de Madrid BH, Taylor P, Li D, Heslop R, Viticheep N, Tan JZ, Shimizu H, Callaghan J, Masiero M, Li JL, Banham AH, Harris AL, Lea SM, Redfield C, Baron M, Handford PA. Whiteman P, et al. Among authors: handford pa. J Biol Chem. 2013 Mar 8;288(10):7305-12. doi: 10.1074/jbc.M112.428854. Epub 2013 Jan 21. J Biol Chem. 2013. PMID: 23339193 Free PMC article.

7

Structural and functional properties of the human notch-1 ligand binding region.

Hambleton S, Valeyev NV, Muranyi A, Knott V, Werner JM, McMichael AJ, Handford PA, Downing AK. Hambleton S, et al. Among authors: handford pa. Structure. 2004 Dec;12(12):2173-83. doi: 10.1016/j.str.2004.09.012. Structure. 2004. PMID: 15576031 Free article.

8

Non-Linear and Flexible Regions of the Human Notch1 Extracellular Domain Revealed by High-Resolution Structural Studies.

Weisshuhn PC, Sheppard D, Taylor P, Whiteman P, Lea SM, Handford PA, Redfield C. Weisshuhn PC, et al. Among authors: handford pa. Structure. 2016 Apr 5;24(4):555-566. doi: 10.1016/j.str.2016.02.010. Epub 2016 Mar 17. Structure. 2016. PMID: 26996961 Free PMC article.

9

A conserved face of the Jagged/Serrate DSL domain is involved in Notch trans-activation and cis-inhibition.

Cordle J, Johnson S, Tay JZ, Roversi P, Wilkin MB, de Madrid BH, Shimizu H, Jensen S, Whiteman P, Jin B, Redfield C, Baron M, Lea SM, Handford PA. Cordle J, et al. Among authors: handford pa. Nat Struct Mol Biol. 2008 Aug;15(8):849-57. doi: 10.1038/nsmb.1457. Epub 2008 Jul 27. Nat Struct Mol Biol. 2008. PMID: 18660822 Free PMC article.

10

Characterisation of fibrillin-1 cDNA clones in a human fibroblast cell line that assembles microfibrils.

Kettle S, Card CM, Hutchinson S, Sykes B, Handford PA. Kettle S, et al. Among authors: handford pa. Int J Biochem Cell Biol. 2000 Feb;32(2):201-14. doi: 10.1016/s1357-2725(99)00120-x. Int J Biochem Cell Biol. 2000. PMID: 10687954

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