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Defective Mitochondrial Cardiolipin Remodeling Dampens HIF-1α Expression in Hypoxia.
Chowdhury A, Aich A, Jain G, Wozny K, Lüchtenborg C, Hartmann M, Bernhard O, Balleiniger M, Alfar EA, Zieseniss A, Toischer K, Guan K, Rizzoli SO, Brügger B, Fischer A, Katschinski DM, Rehling P, Dudek J. Chowdhury A, et al. Among authors: fischer a. Cell Rep. 2018 Oct 16;25(3):561-570.e6. doi: 10.1016/j.celrep.2018.09.057. Cell Rep. 2018. PMID: 30332638 Free PMC article.
KMT2A and KMT2B Mediate Memory Function by Affecting Distinct Genomic Regions.
Kerimoglu C, Sakib MS, Jain G, Benito E, Burkhardt S, Capece V, Kaurani L, Halder R, Agís-Balboa RC, Stilling R, Urbanke H, Kranz A, Stewart AF, Fischer A. Kerimoglu C, et al. Among authors: fischer a. Cell Rep. 2017 Jul 18;20(3):538-548. doi: 10.1016/j.celrep.2017.06.072. Cell Rep. 2017. PMID: 28723559 Free article.
Innate immune memory in the brain shapes neurological disease hallmarks.
Wendeln AC, Degenhardt K, Kaurani L, Gertig M, Ulas T, Jain G, Wagner J, Häsler LM, Wild K, Skodras A, Blank T, Staszewski O, Datta M, Centeno TP, Capece V, Islam MR, Kerimoglu C, Staufenbiel M, Schultze JL, Beyer M, Prinz M, Jucker M, Fischer A, Neher JJ. Wendeln AC, et al. Among authors: fischer a. Nature. 2018 Apr;556(7701):332-338. doi: 10.1038/s41586-018-0023-4. Epub 2018 Apr 11. Nature. 2018. PMID: 29643512 Free PMC article.
miR-182-5p and miR-183-5p Act as GDNF Mimics in Dopaminergic Midbrain Neurons.
Roser AE, Caldi Gomes L, Halder R, Jain G, Maass F, Tönges L, Tatenhorst L, Bähr M, Fischer A, Lingor P. Roser AE, et al. Among authors: fischer a. Mol Ther Nucleic Acids. 2018 Jun 1;11:9-22. doi: 10.1016/j.omtn.2018.01.005. Epub 2018 Feb 2. Mol Ther Nucleic Acids. 2018. PMID: 29858093 Free PMC article.
Alpha-synuclein deregulates the expression of COL4A2 and impairs ER-Golgi function.
Paiva I, Jain G, Lázaro DF, Jerčić KG, Hentrich T, Kerimoglu C, Pinho R, Szegő ÈM, Burkhardt S, Capece V, Halder R, Islam R, Xylaki M, Caldi Gomes LA, Roser AE, Lingor P, Schulze-Hentrich JM, Borovečki F, Fischer A, Outeiro TF. Paiva I, et al. Among authors: fischer a. Neurobiol Dis. 2018 Nov;119:121-135. doi: 10.1016/j.nbd.2018.08.001. Epub 2018 Aug 6. Neurobiol Dis. 2018. PMID: 30092270
Precisely measured protein lifetimes in the mouse brain reveal differences across tissues and subcellular fractions.
Fornasiero EF, Mandad S, Wildhagen H, Alevra M, Rammner B, Keihani S, Opazo F, Urban I, Ischebeck T, Sakib MS, Fard MK, Kirli K, Centeno TP, Vidal RO, Rahman RU, Benito E, Fischer A, Dennerlein S, Rehling P, Feussner I, Bonn S, Simons M, Urlaub H, Rizzoli SO. Fornasiero EF, et al. Among authors: fischer a. Nat Commun. 2018 Oct 12;9(1):4230. doi: 10.1038/s41467-018-06519-0. Nat Commun. 2018. PMID: 30315172 Free PMC article.
The codon sequences predict protein lifetimes and other parameters of the protein life cycle in the mouse brain.
Mandad S, Rahman RU, Centeno TP, Vidal RO, Wildhagen H, Rammner B, Keihani S, Opazo F, Urban I, Ischebeck T, Kirli K, Benito E, Fischer A, Yousefi RY, Dennerlein S, Rehling P, Feussner I, Urlaub H, Bonn S, Rizzoli SO, Fornasiero EF. Mandad S, et al. Among authors: fischer a. Sci Rep. 2018 Nov 15;8(1):16913. doi: 10.1038/s41598-018-35277-8. Sci Rep. 2018. PMID: 30443017 Free PMC article.
5,164 results