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Mrp1 is involved in lipid presentation and iNKT cell activation by Streptococcus pneumoniae.
Chandra S, Gray J, Kiosses WB, Khurana A, Hitomi K, Crosby CM, Chawla A, Fu Z, Zhao M, Veerapen N, Richardson SK, Porcelli SA, Besra G, Howell AR, Sharma S, Peters B, Kronenberg M. Chandra S, et al. Among authors: porcelli sa. Nat Commun. 2018 Oct 15;9(1):4279. doi: 10.1038/s41467-018-06646-8. Nat Commun. 2018. PMID: 30323255 Free PMC article.
The T cell antigen receptor expressed by Valpha14i NKT cells has a unique mode of glycosphingolipid antigen recognition.
Sidobre S, Hammond KJ, Bénazet-Sidobre L, Maltsev SD, Richardson SK, Ndonye RM, Howell AR, Sakai T, Besra GS, Porcelli SA, Kronenberg M. Sidobre S, et al. Among authors: porcelli sa. Proc Natl Acad Sci U S A. 2004 Aug 17;101(33):12254-9. doi: 10.1073/pnas.0404632101. Epub 2004 Aug 10. Proc Natl Acad Sci U S A. 2004. PMID: 15304644 Free PMC article.
Kinetics and cellular site of glycolipid loading control the outcome of natural killer T cell activation.
Im JS, Arora P, Bricard G, Molano A, Venkataswamy MM, Baine I, Jerud ES, Goldberg MF, Baena A, Yu KO, Ndonye RM, Howell AR, Yuan W, Cresswell P, Chang YT, Illarionov PA, Besra GS, Porcelli SA. Im JS, et al. Among authors: porcelli sa. Immunity. 2009 Jun 19;30(6):888-98. doi: 10.1016/j.immuni.2009.03.022. Immunity. 2009. PMID: 19538930 Free PMC article.
A CD1d-dependent antagonist inhibits the activation of invariant NKT cells and prevents development of allergen-induced airway hyperreactivity.
Lombardi V, Stock P, Singh AK, Kerzerho J, Yang W, Sullivan BA, Li X, Shiratsuchi T, Hnatiuk NE, Howell AR, Yu KO, Porcelli SA, Tsuji M, Kronenberg M, Wilson SB, Akbari O. Lombardi V, et al. Among authors: porcelli sa. J Immunol. 2010 Feb 15;184(4):2107-15. doi: 10.4049/jimmunol.0901208. Epub 2010 Jan 18. J Immunol. 2010. PMID: 20083656 Free PMC article.
A rapid fluorescence-based assay for classification of iNKT cell activating glycolipids.
Arora P, Venkataswamy MM, Baena A, Bricard G, Li Q, Veerapen N, Ndonye R, Park JJ, Lee JH, Seo KC, Howell AR, Chang YT, Illarionov PA, Besra GS, Chung SK, Porcelli SA. Arora P, et al. Among authors: porcelli sa. J Am Chem Soc. 2011 Apr 13;133(14):5198-201. doi: 10.1021/ja200070u. Epub 2011 Mar 22. J Am Chem Soc. 2011. PMID: 21425779 Free PMC article.
Glycolipids that elicit IFN-γ-biased responses from natural killer T cells.
Tyznik AJ, Farber E, Girardi E, Birkholz A, Li Y, Chitale S, So R, Arora P, Khurana A, Wang J, Porcelli SA, Zajonc DM, Kronenberg M, Howell AR. Tyznik AJ, et al. Among authors: porcelli sa. Chem Biol. 2011 Dec 23;18(12):1620-30. doi: 10.1016/j.chembiol.2011.10.015. Chem Biol. 2011. PMID: 22195564 Free PMC article.
A Novel Glycolipid Antigen for NKT Cells That Preferentially Induces IFN-γ Production.
Birkholz AM, Girardi E, Wingender G, Khurana A, Wang J, Zhao M, Zahner S, Illarionov PA, Wen X, Li M, Yuan W, Porcelli SA, Besra GS, Zajonc DM, Kronenberg M. Birkholz AM, et al. Among authors: porcelli sa. J Immunol. 2015 Aug 1;195(3):924-33. doi: 10.4049/jimmunol.1500070. Epub 2015 Jun 15. J Immunol. 2015. PMID: 26078271 Free PMC article.
287 results