Single-molecule DNA-mapping and whole-genome sequencing of individual cells.
Marie R, Pedersen JN, Bærlocher L, Koprowska K, Pødenphant M, Sabatel C, Zalkovskij M, Mironov A, Bilenberg B, Ashley N, Flyvbjerg H, Bodmer WF, Kristensen A, Mir KU.
Marie R, et al.
Proc Natl Acad Sci U S A. 2018 Oct 30;115(44):11192-11197. doi: 10.1073/pnas.1804194115. Epub 2018 Oct 15.
Proc Natl Acad Sci U S A. 2018.
PMID: 30322920
Free PMC article.
These chips have modules that collect genomic DNA for sequencing or map genomic structure directly, on-chip, with denaturation-renaturation (D-R) optical mapping [Marie R, et al. (2013) Proc Natl Acad Sci USA 110:4893-4898]. Processing of single cells from th …
These chips have modules that collect genomic DNA for sequencing or map genomic structure directly, on-chip, with denaturation-renaturation …