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Novel 4/3-((4-oxo-5-(2-oxoindolin-3-ylidene)thiazolidin-2-ylidene)amino) benzenesulfonamides: Synthesis, carbonic anhydrase inhibitory activity, anticancer activity and molecular modelling studies.
Eldehna WM, Abo-Ashour MF, Nocentini A, Gratteri P, Eissa IH, Fares M, Ismael OE, Ghabbour HA, Elaasser MM, Abdel-Aziz HA, Supuran CT. Eldehna WM, et al. Eur J Med Chem. 2017 Oct 20;139:250-262. doi: 10.1016/j.ejmech.2017.07.073. Epub 2017 Aug 1. Eur J Med Chem. 2017. PMID: 28802125
3-Hydrazinoisatin-based benzenesulfonamides as novel carbonic anhydrase inhibitors endowed with anticancer activity: Synthesis, in vitro biological evaluation and in silico insights.
Abo-Ashour MF, Eldehna WM, Nocentini A, Bonardi A, Bua S, Ibrahim HS, Elaasser MM, Kryštof V, Jorda R, Gratteri P, Abou-Seri SM, Supuran CT. Abo-Ashour MF, et al. Eur J Med Chem. 2019 Dec 15;184:111768. doi: 10.1016/j.ejmech.2019.111768. Epub 2019 Oct 8. Eur J Med Chem. 2019. PMID: 31629164
Novel [(N-alkyl-3-indolylmethylene)hydrazono]oxindoles arrest cell cycle and induce cell apoptosis by inhibiting CDK2 and Bcl-2: synthesis, biological evaluation and in silico studies.
Al-Warhi T, Abo-Ashour MF, Almahli H, Alotaibi OJ, Al-Sanea MM, Al-Ansary GH, Ahmed HY, Elaasser MM, Eldehna WM, Abdel-Aziz HA. Al-Warhi T, et al. Among authors: abo ashour mf. J Enzyme Inhib Med Chem. 2020 Dec;35(1):1300-1309. doi: 10.1080/14756366.2020.1773814. J Enzyme Inhib Med Chem. 2020. PMID: 32522063 Free PMC article.
3-Methylthiazolo[3,2-a]benzimidazole-benzenesulfonamide conjugates as novel carbonic anhydrase inhibitors endowed with anticancer activity: Design, synthesis, biological and molecular modeling studies.
Alkhaldi AAM, Al-Sanea MM, Nocentini A, Eldehna WM, Elsayed ZM, Bonardi A, Abo-Ashour MF, El-Damasy AK, Abdel-Maksoud MS, Al-Warhi T, Gratteri P, Abdel-Aziz HA, Supuran CT, El-Haggar R. Alkhaldi AAM, et al. Among authors: abo ashour mf. Eur J Med Chem. 2020 Dec 1;207:112745. doi: 10.1016/j.ejmech.2020.112745. Epub 2020 Aug 22. Eur J Med Chem. 2020. PMID: 32877804
Development of 2-oindolin-3-ylidene-indole-3-carbohydrazide derivatives as novel apoptotic and anti-proliferative agents towards colorectal cancer cells.
Eldehna WM, Abo-Ashour MF, Al-Warhi T, Al-Rashood ST, Alharbi A, Ayyad RR, Al-Khayal K, Abdulla M, Abdel-Aziz HA, Ahmad R, El-Haggar R. Eldehna WM, et al. Among authors: abo ashour mf. J Enzyme Inhib Med Chem. 2021 Dec;36(1):319-328. doi: 10.1080/14756366.2020.1862100. J Enzyme Inhib Med Chem. 2021. PMID: 33345633 Free PMC article.
Identification of N-phenyl-2-(phenylsulfonyl)acetamides/propanamides as new SLC-0111 analogues: Synthesis and evaluation of the carbonic anhydrase inhibitory activities.
Elbadawi MM, Eldehna WM, Nocentini A, Abo-Ashour MF, Elkaeed EB, Abdelgawad MA, Alharbi KS, Abdel-Aziz HA, Supuran CT, Gratteri P, Al-Sanea MM. Elbadawi MM, et al. Among authors: abo ashour mf. Eur J Med Chem. 2021 Jun 5;218:113360. doi: 10.1016/j.ejmech.2021.113360. Epub 2021 Mar 13. Eur J Med Chem. 2021. PMID: 33773285
18 results