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Genetically engineered minipigs model the major clinical features of human neurofibromatosis type 1.
Isakson SH, Rizzardi AE, Coutts AW, Carlson DF, Kirstein MN, Fisher J, Vitte J, Williams KB, Pluhar GE, Dahiya S, Widemann BC, Dombi E, Rizvi T, Ratner N, Messiaen L, Stemmer-Rachamimov AO, Fahrenkrug SC, Gutmann DH, Giovannini M, Moertel CL, Largaespada DA, Watson AL. Isakson SH, et al. Among authors: giovannini m. Commun Biol. 2018 Oct 2;1:158. doi: 10.1038/s42003-018-0163-y. eCollection 2018. Commun Biol. 2018. PMID: 30302402 Free PMC article.
Mouse models of neurofibromatosis 1 and 2.
Gutmann DH, Giovannini M. Gutmann DH, et al. Among authors: giovannini m. Neoplasia. 2002 Jul-Aug;4(4):279-90. doi: 10.1038/sj.neo.7900249. Neoplasia. 2002. PMID: 12082543 Free PMC article.
Comparative pathology of nerve sheath tumors in mouse models and humans.
Stemmer-Rachamimov AO, Louis DN, Nielsen GP, Antonescu CR, Borowsky AD, Bronson RT, Burns DK, Cervera P, McLaughlin ME, Reifenberger G, Schmale MC, MacCollin M, Chao RC, Cichowski K, Kalamarides M, Messerli SM, McClatchey AI, Niwa-Kawakita M, Ratner N, Reilly KM, Zhu Y, Giovannini M. Stemmer-Rachamimov AO, et al. Among authors: giovannini m. Cancer Res. 2004 May 15;64(10):3718-24. doi: 10.1158/0008-5472.CAN-03-4079. Cancer Res. 2004. PMID: 15150133
Integrative genomic analyses of neurofibromatosis tumours identify SOX9 as a biomarker and survival gene.
Miller SJ, Jessen WJ, Mehta T, Hardiman A, Sites E, Kaiser S, Jegga AG, Li H, Upadhyaya M, Giovannini M, Muir D, Wallace MR, Lopez E, Serra E, Nielsen GP, Lazaro C, Stemmer-Rachamimov A, Page G, Aronow BJ, Ratner N. Miller SJ, et al. Among authors: giovannini m. EMBO Mol Med. 2009 Jul;1(4):236-48. doi: 10.1002/emmm.200900027. EMBO Mol Med. 2009. PMID: 20049725 Free PMC article.
MEK inhibition exhibits efficacy in human and mouse neurofibromatosis tumors.
Jessen WJ, Miller SJ, Jousma E, Wu J, Rizvi TA, Brundage ME, Eaves D, Widemann B, Kim MO, Dombi E, Sabo J, Hardiman Dudley A, Niwa-Kawakita M, Page GP, Giovannini M, Aronow BJ, Cripe TP, Ratner N. Jessen WJ, et al. Among authors: giovannini m. J Clin Invest. 2013 Jan;123(1):340-7. doi: 10.1172/JCI60578. Epub 2012 Dec 10. J Clin Invest. 2013. PMID: 23221341 Free PMC article. Clinical Trial.
Update from the 2011 International Schwannomatosis Workshop: From genetics to diagnostic criteria.
Plotkin SR, Blakeley JO, Evans DG, Hanemann CO, Hulsebos TJ, Hunter-Schaedle K, Kalpana GV, Korf B, Messiaen L, Papi L, Ratner N, Sherman LS, Smith MJ, Stemmer-Rachamimov AO, Vitte J, Giovannini M. Plotkin SR, et al. Among authors: giovannini m. Am J Med Genet A. 2013 Mar;161A(3):405-16. doi: 10.1002/ajmg.a.35760. Epub 2013 Feb 7. Am J Med Genet A. 2013. PMID: 23401320 Free PMC article.
Therapeutic potential of HSP90 inhibition for neurofibromatosis type 2.
Tanaka K, Eskin A, Chareyre F, Jessen WJ, Manent J, Niwa-Kawakita M, Chen R, White CH, Vitte J, Jaffer ZM, Nelson SF, Rubenstein AE, Giovannini M. Tanaka K, et al. Among authors: giovannini m. Clin Cancer Res. 2013 Jul 15;19(14):3856-70. doi: 10.1158/1078-0432.CCR-12-3167. Epub 2013 May 28. Clin Cancer Res. 2013. PMID: 23714726 Free PMC article.
1,460 results