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Synthetic Lethality of PARP Inhibition and Ionizing Radiation is p53-dependent.
Sizemore ST, Mohammad R, Sizemore GM, Nowsheen S, Yu H, Ostrowski MC, Chakravarti A, Xia F. Sizemore ST, et al. Among authors: chakravarti a. Mol Cancer Res. 2018 Jul;16(7):1092-1102. doi: 10.1158/1541-7786.MCR-18-0106. Epub 2018 Mar 28. Mol Cancer Res. 2018. PMID: 29592899 Free PMC article.
Stromal Platelet-Derived Growth Factor Receptor-β Signaling Promotes Breast Cancer Metastasis in the Brain.
Thies KA, Hammer AM, Hildreth BE 3rd, Steck SA, Spehar JM, Kladney RD, Geisler JA, Das M, Russell LO, Bey JF 4th, Bolyard CM, Pilarski R, Trimboli AJ, Cuitiño MC, Koivisto CS, Stover DG, Schoenfield L, Otero J, Godbout JP, Chakravarti A, Ringel MD, Ramaswamy B, Li Z, Kaur B, Leone G, Ostrowski MC, Sizemore ST, Sizemore GM. Thies KA, et al. Among authors: chakravarti a. Cancer Res. 2021 Feb 1;81(3):606-618. doi: 10.1158/0008-5472.CAN-19-3731. Epub 2020 Apr 23. Cancer Res. 2021. PMID: 32327406 Free PMC article.
The small G-protein RalA promotes progression and metastasis of triple-negative breast cancer.
Thies KA, Cole MW, Schafer RE, Spehar JM, Richardson DS, Steck SA, Das M, Lian AW, Ray A, Shakya R, Knoblaugh SE, Timmers CD, Ostrowski MC, Chakravarti A, Sizemore GM, Sizemore ST. Thies KA, et al. Among authors: chakravarti a. Breast Cancer Res. 2021 Jun 12;23(1):65. doi: 10.1186/s13058-021-01438-3. Breast Cancer Res. 2021. PMID: 34118960 Free PMC article.
Stromal PTEN inhibits the expansion of mammary epithelial stem cells through Jagged-1.
Sizemore GM, Balakrishnan S, Hammer AM, Thies KA, Trimboli AJ, Wallace JA, Sizemore ST, Kladney RD, Woelke SA, Yu L, Fernandez SA, Chakravarti A, Leone G, Ostrowski MC. Sizemore GM, et al. Among authors: chakravarti a. Oncogene. 2017 Apr 20;36(16):2297-2308. doi: 10.1038/onc.2016.383. Epub 2016 Oct 31. Oncogene. 2017. PMID: 27797378 Free PMC article.
Changes in BAI1 and nestin expression are prognostic indicators for survival and metastases in breast cancer and provide opportunities for dual targeted therapies.
Meisen WH, Dubin S, Sizemore ST, Mathsyaraja H, Thies K, Lehman NL, Boyer P, Jaime-Ramirez AC, Elder JB, Powell K, Chakravarti A, Ostrowski MC, Kaur B. Meisen WH, et al. Among authors: chakravarti a. Mol Cancer Ther. 2015 Jan;14(1):307-14. doi: 10.1158/1535-7163.MCT-14-0659. Epub 2014 Nov 5. Mol Cancer Ther. 2015. PMID: 25376607 Free PMC article.
A Novel miR-146a-POU3F2/SMARCA5 Pathway Regulates Stemness and Therapeutic Response in Glioblastoma.
Cui T, Bell EH, McElroy J, Liu K, Sebastian E, Johnson B, Gulati PM, Becker AP, Gray A, Geurts M, Subedi D, Yang L, Fleming JL, Meng W, Barnholtz-Sloan JS, Venere M, Wang QE, Robe PA, Haque SJ, Chakravarti A. Cui T, et al. Among authors: chakravarti a. Mol Cancer Res. 2021 Jan;19(1):48-60. doi: 10.1158/1541-7786.MCR-20-0353. Epub 2020 Sep 24. Mol Cancer Res. 2021. PMID: 32973101
925 results