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Control of mRNA splicing by noncoding intragenic RNA elements that evoke a cellular stress response.
Int J Biochem Cell Biol. 2018 Dec;105:20-23. doi: 10.1016/j.biocel.2018.09.021. Epub 2018 Sep 30.
Int J Biochem Cell Biol. 2018.
PMID: 30282053
Review.
Dynamic refolding of IFN-gamma mRNA enables it to function as PKR activator and translation template.
Cohen-Chalamish S, Hasson A, Weinberg D, Namer LS, Banai Y, Osman F, Kaempfer R.
Cohen-Chalamish S, et al. Among authors: namer ls.
Nat Chem Biol. 2009 Dec;5(12):896-903. doi: 10.1038/nchembio.234. Epub 2009 Oct 4.
Nat Chem Biol. 2009.
PMID: 19801993
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PKR activation and eIF2α phosphorylation mediate human globin mRNA splicing at spliceosome assembly.
Ilan L, Osman F, Namer LS, Eliahu E, Cohen-Chalamish S, Ben-Asouli Y, Banai Y, Kaempfer R.
Ilan L, et al. Among authors: namer ls.
Cell Res. 2017 May;27(5):688-704. doi: 10.1038/cr.2017.39. Epub 2017 Apr 4.
Cell Res. 2017.
PMID: 28374749
Free PMC article.
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An Ancient Pseudoknot in TNF-α Pre-mRNA Activates PKR, Inducing eIF2α Phosphorylation that Potently Enhances Splicing.
Namer LS, Osman F, Banai Y, Masquida B, Jung R, Kaempfer R.
Namer LS, et al.
Cell Rep. 2017 Jul 5;20(1):188-200. doi: 10.1016/j.celrep.2017.06.035.
Cell Rep. 2017.
PMID: 28683312
Free article.
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Control of mRNA Splicing by Intragenic RNA Activators of Stress Signaling: Potential Implications for Human Disease.
Kaempfer R, Ilan L, Cohen-Chalamish S, Turgeman O, Namer LS, Osman F.
Kaempfer R, et al. Among authors: namer ls.
Front Genet. 2019 May 14;10:464. doi: 10.3389/fgene.2019.00464. eCollection 2019.
Front Genet. 2019.
PMID: 31139209
Free PMC article.
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Intragenic regulation of SOCS3 isoforms.
Klepsch O, Namer LS, Köhler N, Kaempfer R, Dittrich A, Schaper F.
Klepsch O, et al. Among authors: namer ls.
Cell Commun Signal. 2019 Jun 25;17(1):70. doi: 10.1186/s12964-019-0379-6.
Cell Commun Signal. 2019.
PMID: 31238931
Free PMC article.
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HIV co-opts a cellular antiviral mechanism, activation of stress kinase PKR by its RNA, to enable splicing of rev/tat mRNA.
Namer LS, Harwig A, Heynen SP, Das AT, Berkhout B, Kaempfer R.
Namer LS, et al.
Cell Biosci. 2023 Feb 11;13(1):28. doi: 10.1186/s13578-023-00972-1.
Cell Biosci. 2023.
PMID: 36774495
Free PMC article.
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