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Extrapolation of in vitro structural alerts for mutagenicity to the in vivo endpoint.
Mutagenesis. 2019 Mar 6;34(1):111-121. doi: 10.1093/mutage/gey030.
Mutagenesis. 2019.
PMID: 30281100
Utility of published DNA reactivity alerts.
Myden A, Guesne SJ, Cayley A, Williams RV.
Myden A, et al. Among authors: guesne sj.
Regul Toxicol Pharmacol. 2017 Aug;88:77-86. doi: 10.1016/j.yrtph.2017.05.016. Epub 2017 May 23.
Regul Toxicol Pharmacol. 2017.
PMID: 28549899
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Mind your prevalence!
Guesné SJJ, Hanser T, Werner S, Boobier S, Scott S.
Guesné SJJ, et al.
J Cheminform. 2024 Apr 15;16(1):43. doi: 10.1186/s13321-024-00837-w.
J Cheminform. 2024.
PMID: 38622648
Free PMC article.
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The Asymmetric Aza-silyl-Prins Reaction: Synthesis of Enantiopure Piperidines.
Mittapalli RR, Guesné SJJ, Parker RJ, Klooster WT, Coles SJ, Skidmore J, Dobbs AP.
Mittapalli RR, et al. Among authors: guesne sjj.
Org Lett. 2019 Jan 18;21(2):350-355. doi: 10.1021/acs.orglett.8b03283. Epub 2018 Dec 28.
Org Lett. 2019.
PMID: 30592613
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Synthesis of Azabicycles via Cascade Aza-Prins Reactions: Accessing the Indolizidine and Quinolizidine Cores.
Chio FK, Guesné SJ, Hassall L, McGuire T, Dobbs AP.
Chio FK, et al. Among authors: guesne sj.
J Org Chem. 2015 Oct 16;80(20):9868-80. doi: 10.1021/acs.joc.5b01301. Epub 2015 Oct 2.
J Org Chem. 2015.
PMID: 26375043
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A detailed investigation of the aza-Prins reaction.
Dobbs AP, Guesné SJ, Parker RJ, Skidmore J, Stephenson RA, Hursthouse MB.
Dobbs AP, et al. Among authors: guesne sj.
Org Biomol Chem. 2010 Mar 7;8(5):1064-80. doi: 10.1039/b915797b. Epub 2010 Jan 5.
Org Biomol Chem. 2010.
PMID: 20165797
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A versatile indium trichloride mediated Prins-type reaction to unsaturated heterocycles.
Dobbs AP, Guesné SJ, Martinović S, Coles SJ, Hursthouse MB.
Dobbs AP, et al. Among authors: guesne sj.
J Org Chem. 2003 Oct 3;68(20):7880-3. doi: 10.1021/jo034981k.
J Org Chem. 2003.
PMID: 14510570
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