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AKT and AMP-activated protein kinase regulate TBC1D1 through phosphorylation and its interaction with the cytosolic tail of insulin-regulated aminopeptidase IRAP.
J Biol Chem. 2018 Nov 16;293(46):17853-17862. doi: 10.1074/jbc.RA118.005040. Epub 2018 Oct 1.
J Biol Chem. 2018.
PMID: 30275018
Free PMC article.
Contraction-Mediated Glucose Transport in Skeletal Muscle Is Regulated by a Framework of AMPK, TBC1D1/4, and Rac1.
de Wendt C, Espelage L, Eickelschulte S, Springer C, Toska L, Scheel A, Bedou AD, Benninghoff T, Cames S, Stermann T, Chadt A, Al-Hasani H.
de Wendt C, et al.
Diabetes. 2021 Dec;70(12):2796-2809. doi: 10.2337/db21-0587. Epub 2021 Sep 24.
Diabetes. 2021.
PMID: 34561225
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“Deletion of both Rab-GTPase–activating proteins TBC1D1 and TBC1D4 in mice eliminates insulin- and AICAR-stimulated glucose transport [corrected].
Chadt A, Immisch A, de Wendt C, Springer C, Zhou Z, Stermann T, Holman GD, Loffing-Cueni D, Loffing J, Joost HG, Al-Hasani H.
Chadt A, et al. Among authors: de wendt c.
Diabetes. 2015 Mar;64(3):746-59. doi: 10.2337/db14-0368. Epub 2014 Sep 23.
Diabetes. 2015.
PMID: 25249576
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Deletion of the RabGAP TBC1D1 Leads to Enhanced Insulin Secretion and Fatty Acid Oxidation in Islets From Male Mice.
Stermann T, Menzel F, Weidlich C, Jeruschke K, Weiss J, Altenhofen D, Benninghoff T, Pujol A, Bosch F, Rustenbeck I, Ouwens DM, Thoresen GH, de Wendt C, Lebek S, Schallschmidt T, Kragl M, Lammert E, Chadt A, Al-Hasani H.
Stermann T, et al. Among authors: de wendt c.
Endocrinology. 2018 Apr 1;159(4):1748-1761. doi: 10.1210/en.2018-00087.
Endocrinology. 2018.
PMID: 29481597
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TBC1D4 Is Necessary for Enhancing Muscle Insulin Sensitivity in Response to AICAR and Contraction.
Kjøbsted R, Chadt A, Jørgensen NO, Kido K, Larsen JK, de Wendt C, Al-Hasani H, Wojtaszewski JFP.
Kjøbsted R, et al. Among authors: de wendt c.
Diabetes. 2019 Sep;68(9):1756-1766. doi: 10.2337/db18-0769. Epub 2019 Jun 7.
Diabetes. 2019.
PMID: 31175100
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Histone deacetylase 5 regulates interleukin 6 secretion and insulin action in skeletal muscle.
Klymenko O, Brecklinghaus T, Dille M, Springer C, de Wendt C, Altenhofen D, Binsch C, Knebel B, Scheller J, Hardt C, Herwig R, Chadt A, Pfluger PT, Al-Hasani H, Kabra DG.
Klymenko O, et al. Among authors: de wendt c.
Mol Metab. 2020 Dec;42:101062. doi: 10.1016/j.molmet.2020.101062. Epub 2020 Aug 6.
Mol Metab. 2020.
PMID: 32771698
Free PMC article.
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Deletion of both Rab-GTPase-activating proteins TBC14KO and TBC1D4 in mice eliminates insulin- and AICAR-stimulated glucose transport. Diabetes 2015;64:746-759.
Chadt A, Immisch A, de Wendt C, Springer C, Zhou Z, Stermann T, Holman GD, Loffing-Cueni D, Loffing J, Joost HG, Al-Hasani H.
Chadt A, et al. Among authors: de wendt c.
Diabetes. 2015 Apr;64(4):1492. doi: 10.2337/db15-er04.
Diabetes. 2015.
PMID: 25805765
Free article.
No abstract available.
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