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A kinome-wide screen using a NanoLuc LATS luminescent biosensor identifies ALK as a novel regulator of the Hippo pathway in tumorigenesis and immune evasion.
Nouri K, Azad T, Lightbody E, Khanal P, Nicol CJ, Yang X. Nouri K, et al. FASEB J. 2019 Nov;33(11):12487-12499. doi: 10.1096/fj.201901343R. Epub 2019 Aug 20. FASEB J. 2019. PMID: 31431076 Free PMC article.
In summary, we have developed a new LATS BS for cancer biology and therapeutics research and uncovered a novel ALK-LATS-YAP/TAZ signaling axis that may play important roles in cancer and possibly other biologic processes.-Nouri, K., Azad, T., Lightbody, E., Khanal, …
In summary, we have developed a new LATS BS for cancer biology and therapeutics research and uncovered a novel ALK-LATS-YAP/TAZ signaling ax …
Nanoluciferase complementation-based bioreporter reveals the importance of N-linked glycosylation of SARS-CoV-2 S for viral entry.
Azad T, Singaravelu R, Taha Z, Jamieson TR, Boulton S, Crupi MJF, Martin NT, Fekete EEF, Poutou J, Ghahremani M, Pelin A, Nouri K, Rezaei R, Marshall CB, Enomoto M, Arulanandam R, Alluqmani N, Samson R, Gingras AC, Cameron DW, Greer PA, Ilkow CS, Diallo JS, Bell JC. Azad T, et al. Among authors: nouri k. Mol Ther. 2021 Jun 2;29(6):1984-2000. doi: 10.1016/j.ymthe.2021.02.007. Epub 2021 Feb 10. Mol Ther. 2021. PMID: 33578036 Free PMC article.
Implications for SARS-CoV-2 Vaccine Design: Fusion of Spike Glycoprotein Transmembrane Domain to Receptor-Binding Domain Induces Trimerization.
Azad T, Singaravelu R, Crupi MJF, Jamieson T, Dave J, Brown EEF, Rezaei R, Taha Z, Boulton S, Martin NT, Surendran A, Poutou J, Ghahremani M, Nouri K, Whelan JT, Duong J, Tucker S, Diallo JS, Bell JC, Ilkow CS. Azad T, et al. Among authors: nouri k. Membranes (Basel). 2020 Aug 30;10(9):215. doi: 10.3390/membranes10090215. Membranes (Basel). 2020. PMID: 32872641 Free PMC article.
430 results