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Engineered hexavalent Fc proteins with enhanced Fc-gamma receptor avidity provide insights into immune-complex interactions.
Rowley TF, Peters SJ, Aylott M, Griffin R, Davies NL, Healy LJ, Cutler RM, Eddleston A, Pither TL, Sopp JM, Zaccheo O, Fossati G, Cain K, Ventom AM, Hailu H, Ward EJ, Sherington J, Brennan FR, Fallah-Arani F, Humphreys DP. Rowley TF, et al. Among authors: ward ej. Commun Biol. 2018 Sep 14;1:146. doi: 10.1038/s42003-018-0149-9. eCollection 2018. Commun Biol. 2018. PMID: 30272022 Free PMC article.
Multivalent Fcγ-receptor engagement by a hexameric Fc-fusion protein triggers Fcγ-receptor internalisation and modulation of Fcγ-receptor functions.
Qureshi OS, Rowley TF, Junker F, Peters SJ, Crilly S, Compson J, Eddleston A, Björkelund H, Greenslade K, Parkinson M, Davies NL, Griffin R, Pither TL, Cain K, Christodoulou L, Staelens L, Ward E, Tibbitts J, Kiessling A, Smith B, Brennan FR, Malmqvist M, Fallah-Arani F, Humphreys DP. Qureshi OS, et al. Sci Rep. 2017 Dec 6;7(1):17049. doi: 10.1038/s41598-017-17255-8. Sci Rep. 2017. PMID: 29213127 Free PMC article.
Discovery of a Potent, Orally Bioavailable PI4KIIIβ Inhibitor (UCB9608) Able To Significantly Prolong Allogeneic Organ Engraftment in Vivo.
Reuberson J, Horsley H, Franklin RJ, Ford D, Neuss J, Brookings D, Huang Q, Vanderhoydonck B, Gao LJ, Jang MY, Herdewijn P, Ghawalkar A, Fallah-Arani F, Khan AR, Henshall J, Jairaj M, Malcolm S, Ward E, Shuttleworth L, Lin Y, Li S, Louat T, Waer M, Herman J, Payne A, Ceska T, Doyle C, Pitt W, Calmiano M, Augustin M, Steinbacher S, Lammens A, Allen R. Reuberson J, et al. J Med Chem. 2018 Aug 9;61(15):6705-6723. doi: 10.1021/acs.jmedchem.8b00521. Epub 2018 Jul 19. J Med Chem. 2018. PMID: 29952567
Practical Guide to Measuring Wetland Carbon Pools and Fluxes.
Bansal S, Creed IF, Tangen BA, Bridgham SD, Desai AR, Krauss KW, Neubauer SC, Noe GB, Rosenberry DO, Trettin C, Wickland KP, Allen ST, Arias-Ortiz A, Armitage AR, Baldocchi D, Banerjee K, Bastviken D, Berg P, Bogard MJ, Chow AT, Conner WH, Craft C, Creamer C, DelSontro T, Duberstein JA, Eagle M, Fennessy MS, Finkelstein SA, Göckede M, Grunwald S, Halabisky M, Herbert E, Jahangir MMR, Johnson OF, Jones MC, Kelleway JJ, Knox S, Kroeger KD, Kuehn KA, Lobb D, Loder AL, Ma S, Maher DT, McNicol G, Meier J, Middleton BA, Mills C, Mistry P, Mitra A, Mobilian C, Nahlik AM, Newman S, O'Connell JL, Oikawa P, van der Burg MP, Schutte CA, Song C, Stagg CL, Turner J, Vargas R, Waldrop MP, Wallin MB, Wang ZA, Ward EJ, Willard DA, Yarwood S, Zhu X. Bansal S, et al. Among authors: ward ej. Wetlands (Wilmington). 2023;43(8):105. doi: 10.1007/s13157-023-01722-2. Epub 2023 Nov 28. Wetlands (Wilmington). 2023. PMID: 38037553 Free PMC article. Review.
Species redistribution creates unequal outcomes for multispecies fisheries under projected climate change.
Liu OR, Ward EJ, Anderson SC, Andrews KS, Barnett LAK, Brodie S, Carroll G, Fiechter J, Haltuch MA, Harvey CJ, Hazen EL, Hernvann PY, Jacox M, Kaplan IC, Matson S, Norman K, Pozo Buil M, Selden RL, Shelton A, Samhouri JF. Liu OR, et al. Among authors: ward ej. Sci Adv. 2023 Aug 18;9(33):eadg5468. doi: 10.1126/sciadv.adg5468. Epub 2023 Aug 18. Sci Adv. 2023. PMID: 37595038 Free PMC article.
142 results