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Engineered hexavalent Fc proteins with enhanced Fc-gamma receptor avidity provide insights into immune-complex interactions.
Commun Biol. 2018 Sep 14;1:146. doi: 10.1038/s42003-018-0149-9. eCollection 2018.
Commun Biol. 2018.
PMID: 30272022
Free PMC article.
On-target IgG hexamerisation driven by a C-terminal IgM tail-piece fusion variant confers augmented complement activation.
Sopp JM, Peters SJ, Rowley TF, Oldham RJ, James S, Mockridge I, French RR, Turner A, Beers SA, Humphreys DP, Cragg MS.
Sopp JM, et al.
Commun Biol. 2021 Sep 2;4(1):1031. doi: 10.1038/s42003-021-02513-3.
Commun Biol. 2021.
PMID: 34475514
Free PMC article.
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Impact of Human FcγR Gene Polymorphisms on IgG-Triggered Cytokine Release: Critical Importance of Cell Assay Format.
Hussain K, Hargreaves CE, Rowley TF, Sopp JM, Latham KV, Bhatta P, Sherington J, Cutler RM, Humphreys DP, Glennie MJ, Strefford JC, Cragg MS.
Hussain K, et al. Among authors: sopp jm.
Front Immunol. 2019 Mar 7;10:390. doi: 10.3389/fimmu.2019.00390. eCollection 2019.
Front Immunol. 2019.
PMID: 30899264
Free PMC article.
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Deleting Malignant B Cells With Second-Generation Anti-CD20 Antibodies.
Sopp J, Cragg MS.
Sopp J, et al.
J Clin Oncol. 2018 Aug 1;36(22):2323-2325. doi: 10.1200/JCO.2018.78.7390. Epub 2018 Jun 12.
J Clin Oncol. 2018.
PMID: 29894272
No abstract available.
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