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mTORC1 Prevents Epithelial Damage During Inflammation and Inhibits Colitis-Associated Colorectal Cancer Development.
Gutiérrez-Martínez IZ, Rubio JF, Piedra-Quintero ZL, Lopez-Mendez O, Serrano C, Reyes-Maldonado E, Salinas-Lara C, Betanzos A, Shibayama M, Silva-Olivares A, Candelario-Martinez A, Meraz-Ríos MA, Schnoor M, Villegas-Sepúlveda N, Nava P. Gutiérrez-Martínez IZ, et al. Transl Oncol. 2019 Jan;12(1):24-35. doi: 10.1016/j.tranon.2018.08.016. Epub 2018 Sep 25. Transl Oncol. 2019. PMID: 30265974 Free PMC article.
The pro-inflammatory cytokines IFNγ/TNFα increase chromogranin A-positive neuroendocrine cells in the colonic epithelium.
Hernández-Trejo JA, Suárez-Pérez D, Gutiérrez-Martínez IZ, Fernandez-Vargas OE, Serrano C, Candelario-Martínez AA, Meraz-Ríos MA, Citalán-Madrid AF, Hernández-Ruíz M, Reyes-Maldonado E, Valle-Rios R, Feintuch-Unger JH, Schnoor M, Villegas-Sepúlveda N, Medina-Contreras O, Nava P. Hernández-Trejo JA, et al. Biochem J. 2016 Nov 1;473(21):3805-3818. doi: 10.1042/BCJ20160390. Epub 2016 Aug 18. Biochem J. 2016. PMID: 27538402
pVHL suppresses Akt/β-catenin-mediated cell proliferation by inhibiting 14-3-3ζ expression.
Castañeda A, Serrano C, Hernández-Trejo JA, Gutiérrez-Martínez IZ, Montejo-López W, Gómez-Suárez M, Hernández-Ruiz M, Betanzos A, Candelario-Martínez A, Romo-Parra H, Arias-Montaño JA, Schnoor M, Meraz Ríos MA, Gutierrez-Castillo ME, Martínez-Dávila IA, Villegas-Sepúlveda N, Martinez-Fong D, Nava P. Castañeda A, et al. Biochem J. 2017 Jul 27;474(16):2679-2689. doi: 10.1042/BCJ20161097. Biochem J. 2017. PMID: 28666999
Use of STAT6 Phosphorylation Inhibitor and Trimethylglycine as New Adjuvant Therapies for 5-Fluorouracil in Colitis-Associated Tumorigenesis.
Mendoza-Rodríguez MG, Sánchez-Barrera CÁ, Callejas BE, García-Castillo V, Beristain-Terrazas DL, Delgado-Buenrostro NL, Chirino YI, León-Cabrera SA, Rodríguez-Sosa M, Gutierrez-Cirlos EB, Pérez-Plasencia C, Vaca-Paniagua F, Meraz-Ríos MA, Terrazas LI. Mendoza-Rodríguez MG, et al. Int J Mol Sci. 2020 Mar 20;21(6):2130. doi: 10.3390/ijms21062130. Int J Mol Sci. 2020. PMID: 32244885 Free PMC article.
The Nurr7 agonist Cytosporone B differentially regulates inflammatory responses in human polarized macrophages.
Patiño-Martínez E, Solís-Barbosa MA, Santana E, González-Domínguez E, Segovia-Gamboa NC, Meraz-Ríos MA, Córdova EJ, Valdés J, Corbí ÁL, Sánchez-Torres C. Patiño-Martínez E, et al. Among authors: meraz rios ma. Immunobiology. 2022 Nov;227(6):152299. doi: 10.1016/j.imbio.2022.152299. Epub 2022 Nov 2. Immunobiology. 2022. PMID: 36370518
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