Ryan GM - Search Results

1

Liposomal Formulations to Modulate the Tumour Microenvironment and Antitumour Immune Response.

Gilabert-Oriol R, Ryan GM, Leung AWY, Firmino NS, Bennewith KL, Bally MB. Gilabert-Oriol R, et al. Among authors: ryan gm. Int J Mol Sci. 2018 Sep 26;19(10):2922. doi: 10.3390/ijms19102922. Int J Mol Sci. 2018. PMID: 30261606 Free PMC article. Review.

2

Copper (II) complexes of bidentate ligands exhibit potent anti-cancer activity regardless of platinum sensitivity status.

Wehbe M, Lo C, Leung AWY, Dragowska WH, Ryan GM, Bally MB. Wehbe M, et al. Among authors: ryan gm. Invest New Drugs. 2017 Dec;35(6):682-690. doi: 10.1007/s10637-017-0488-2. Epub 2017 Jul 21. Invest New Drugs. 2017. PMID: 28733701 Free PMC article.

3

DMPC/Chol liposomal copper CX5461 is therapeutically superior to a DSPC/Chol formulation.

Leung AWY, Chen KTJ, Ryan GM, Anantha M, Wretham N, Nosrati Z, Heroux D, Wang L, Chow N, Dai Z, Bally MB. Leung AWY, et al. Among authors: ryan gm. J Control Release. 2022 May;345:75-90. doi: 10.1016/j.jconrel.2022.03.004. Epub 2022 Mar 5. J Control Release. 2022. PMID: 35259461 Free article.

4

Optimal PEGylation can improve the exposure of interferon in the lungs following pulmonary administration.

Mcleod VM, Chan LJ, Ryan GM, Porter CJ, Kaminskas LM. Mcleod VM, et al. Among authors: ryan gm. J Pharm Sci. 2015 Apr;104(4):1421-30. doi: 10.1002/jps.24353. Epub 2015 Jan 28. J Pharm Sci. 2015. PMID: 25631360

5

PEGylated polylysine dendrimers increase lymphatic exposure to doxorubicin when compared to PEGylated liposomal and solution formulations of doxorubicin.

Ryan GM, Kaminskas LM, Bulitta JB, McIntosh MP, Owen DJ, Porter CJH. Ryan GM, et al. J Control Release. 2013 Nov 28;172(1):128-136. doi: 10.1016/j.jconrel.2013.08.004. Epub 2013 Aug 13. J Control Release. 2013. PMID: 23954628

6

Pulmonary administration of PEGylated polylysine dendrimers: absorption from the lung versus retention within the lung is highly size-dependent.

Ryan GM, Kaminskas LM, Kelly BD, Owen DJ, McIntosh MP, Porter CJ. Ryan GM, et al. Mol Pharm. 2013 Aug 5;10(8):2986-95. doi: 10.1021/mp400091n. Epub 2013 Jun 26. Mol Pharm. 2013. PMID: 23750747

7

Lymphatic transport and lymph node targeting of methotrexate-conjugated PEGylated dendrimers are enhanced by reducing the length of the drug linker or masking interactions with the injection site.

Ryan GM, McLeod VM, Mehta D, Kelly BD, Stanislawski PC, Owen DJ, Kaminskas LM, Porter CJH. Ryan GM, et al. Nanomedicine. 2017 Nov;13(8):2485-2494. doi: 10.1016/j.nano.2017.08.003. Epub 2017 Aug 15. Nanomedicine. 2017. PMID: 28821463

8

Methotrexate-conjugated PEGylated dendrimers show differential patterns of deposition and activity in tumor-burdened lymph nodes after intravenous and subcutaneous administration in rats.

Kaminskas LM, McLeod VM, Ascher DB, Ryan GM, Jones S, Haynes JM, Trevaskis NL, Chan LJ, Sloan EK, Finnin BA, Williamson M, Velkov T, Williams ED, Kelly BD, Owen DJ, Porter CJ. Kaminskas LM, et al. Among authors: ryan gm. Mol Pharm. 2015 Feb 2;12(2):432-43. doi: 10.1021/mp500531e. Epub 2015 Jan 20. Mol Pharm. 2015. PMID: 25485615

9

Nano-chemotherapeutics: maximising lymphatic drug exposure to improve the treatment of lymph-metastatic cancers.

Ryan GM, Kaminskas LM, Porter CJ. Ryan GM, et al. J Control Release. 2014 Nov 10;193:241-56. doi: 10.1016/j.jconrel.2014.04.051. Epub 2014 May 5. J Control Release. 2014. PMID: 24801249 Review.

10

A Comparison of the Pharmacokinetics and Pulmonary Lymphatic Exposure of a Generation 4 PEGylated Dendrimer Following Intravenous and Aerosol Administration to Rats and Sheep.

Ryan GM, Bischof RJ, Enkhbaatar P, McLeod VM, Chan LJ, Jones SA, Owen DJ, Porter CJ, Kaminskas LM. Ryan GM, et al. Pharm Res. 2016 Feb;33(2):510-25. doi: 10.1007/s11095-015-1806-z. Epub 2015 Oct 20. Pharm Res. 2016. PMID: 26486513

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