Zhuang X - Search Results

1

Metabonomics reveals that triclocarban affects liver metabolism by affecting glucose metabolism, β-oxidation of fatty acids, and the TCA cycle in male mice.

Li W, Zhang W, Chang M, Ren J, Xie W, Chen H, Zhang Z, Zhuang X, Shen G, Li H. Li W, et al. Among authors: zhuang x. Toxicol Lett. 2018 Dec 15;299:76-85. doi: 10.1016/j.toxlet.2018.09.011. Epub 2018 Sep 24. Toxicol Lett. 2018. PMID: 30261223

2

A simplified model to predict P-glycoprotein interacting drugs from 3D molecular interaction field.

Zhuang XM, Xiao JH, Li JT, Zhang ZQ, Ruan JX. Zhuang XM, et al. Int J Pharm. 2006 Feb 17;309(1-2):109-14. doi: 10.1016/j.ijpharm.2005.11.009. Epub 2005 Dec 20. Int J Pharm. 2006. PMID: 16376035

3

[Evaluation of P-glycoprotein mediated in vitro loperamide biliary excretion with sandwich-cultured rat hepatocytes model].

Shen GL, Zhuang XM, Yuan M, Sun HX, Li H. Shen GL, et al. Yao Xue Xue Bao. 2012 Apr;47(4):459-65. Yao Xue Xue Bao. 2012. PMID: 22799027 Chinese.

4

Simultaneous determination of triptolide and its prodrug MC002 in dog blood by LC-MS/MS and its application in pharmacokinetic studies.

Zhuang XM, Liu PX, Zhang YJ, Li CK, Li Y, Wang J, Zhou L, Zhang ZQ. Zhuang XM, et al. J Ethnopharmacol. 2013 Oct 28;150(1):131-7. doi: 10.1016/j.jep.2013.08.018. Epub 2013 Aug 29. J Ethnopharmacol. 2013. PMID: 23994469

5

Assessment of the roles of P-glycoprotein and cytochrome P450 in triptolide-induced liver toxicity in sandwich-cultured rat hepatocyte model.

Zhuang XM, Shen GL, Xiao WB, Tan Y, Lu C, Li H. Zhuang XM, et al. Drug Metab Dispos. 2013 Dec;41(12):2158-65. doi: 10.1124/dmd.113.054056. Epub 2013 Sep 24. Drug Metab Dispos. 2013. PMID: 24065861

6

Simultaneous quantification of L-tetrahydropalmatine and its urine metabolites by ultra high performance liquid chromatography with tandem mass spectrometry.

Xiao W, Zhuang X, Shen G, Zhong Y, Yuan M, Li H. Xiao W, et al. Among authors: zhuang x. J Sep Sci. 2014 Mar;37(6):696-703. doi: 10.1002/jssc.201301352. Epub 2014 Feb 19. J Sep Sci. 2014. PMID: 24453165

7

Characterization of preclinical in vitro and in vivo ADME properties and prediction of human PK using a physiologically based pharmacokinetic model for YQA-14, a new dopamine D3 receptor antagonist candidate for treatment of drug addiction.

Liu F, Zhuang X, Yang C, Li Z, Xiong S, Zhang Z, Li J, Lu C, Zhang Z. Liu F, et al. Among authors: zhuang x. Biopharm Drug Dispos. 2014 Jul;35(5):296-307. doi: 10.1002/bdd.1897. Epub 2014 Apr 13. Biopharm Drug Dispos. 2014. PMID: 24647883

8

Role of CYP3A in regulating hepatic clearance and hepatotoxicity of triptolide in rat liver microsomes and sandwich-cultured hepatocytes.

Shen G, Zhuang X, Xiao W, Kong L, Tan Y, Li H. Shen G, et al. Among authors: zhuang x. Food Chem Toxicol. 2014 Sep;71:90-6. doi: 10.1016/j.fct.2014.05.020. Epub 2014 Jun 6. Food Chem Toxicol. 2014. PMID: 24910460

9

[Investigation of metabolic kinetics and reaction phenotyping of ligustrazin by using liver microsomes and recombinant human enzymes].

Tan Y, Zhuang XM, Shen GL, Li H, Gao Y. Tan Y, et al. Yao Xue Xue Bao. 2014 Mar;49(3):374-9. Yao Xue Xue Bao. 2014. PMID: 24961110 Chinese.

10

P-Glycoprotein (ABCB1) limits the brain distribution of YQA-14, a novel dopamine D3 receptor antagonist.

Liu F, Wang X, Li Z, Li J, Zhuang X, Zhang Z. Liu F, et al. Among authors: zhuang x. Chem Pharm Bull (Tokyo). 2015;63(7):512-8. doi: 10.1248/cpb.c15-00089. Chem Pharm Bull (Tokyo). 2015. PMID: 26133067 Free article.

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