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Reprogramming miRNAs global expression orchestrates development of drug resistance in BRAF mutated melanoma.
Fattore L, Ruggiero CF, Pisanu ME, Liguoro D, Cerri A, Costantini S, Capone F, Acunzo M, Romano G, Nigita G, Mallardo D, Ragone C, Carriero MV, Budillon A, Botti G, Ascierto PA, Mancini R, Ciliberto G. Fattore L, et al. Among authors: pisanu me. Cell Death Differ. 2019 Jul;26(7):1267-1282. doi: 10.1038/s41418-018-0205-5. Epub 2018 Sep 25. Cell Death Differ. 2019. PMID: 30254376 Free PMC article.
Activation of an early feedback survival loop involving phospho-ErbB3 is a general response of melanoma cells to RAF/MEK inhibition and is abrogated by anti-ErbB3 antibodies.
Fattore L, Marra E, Pisanu ME, Noto A, de Vitis C, Belleudi F, Aurisicchio L, Mancini R, Torrisi MR, Ascierto PA, Ciliberto G. Fattore L, et al. Among authors: pisanu me. J Transl Med. 2013 Jul 27;11:180. doi: 10.1186/1479-5876-11-180. J Transl Med. 2013. PMID: 23890105 Free PMC article.
Combination of antibodies directed against different ErbB3 surface epitopes prevents the establishment of resistance to BRAF/MEK inhibitors in melanoma.
Fattore L, Malpicci D, Marra E, Belleudi F, Noto A, De Vitis C, Pisanu ME, Coluccia P, Camerlingo R, Roscilli G, Ribas A, Di Napoli A, Torrisi MR, Aurisicchio L, Ascierto PA, Mancini R, Ciliberto G. Fattore L, et al. Among authors: pisanu me. Oncotarget. 2015 Sep 22;6(28):24823-41. doi: 10.18632/oncotarget.4485. Oncotarget. 2015. PMID: 26208478 Free PMC article.
miR-579-3p controls melanoma progression and resistance to target therapy.
Fattore L, Mancini R, Acunzo M, Romano G, Laganà A, Pisanu ME, Malpicci D, Madonna G, Mallardo D, Capone M, Fulciniti F, Mazzucchelli L, Botti G, Croce CM, Ascierto PA, Ciliberto G. Fattore L, et al. Among authors: pisanu me. Proc Natl Acad Sci U S A. 2016 Aug 23;113(34):E5005-13. doi: 10.1073/pnas.1607753113. Epub 2016 Aug 8. Proc Natl Acad Sci U S A. 2016. PMID: 27503895 Free PMC article.
Stearoyl-CoA-desaturase 1 regulates lung cancer stemness via stabilization and nuclear localization of YAP/TAZ.
Noto A, De Vitis C, Pisanu ME, Roscilli G, Ricci G, Catizone A, Sorrentino G, Chianese G, Taglialatela-Scafati O, Trisciuoglio D, Del Bufalo D, Di Martile M, Di Napoli A, Ruco L, Costantini S, Jakopin Z, Budillon A, Melino G, Del Sal G, Ciliberto G, Mancini R. Noto A, et al. Among authors: pisanu me. Oncogene. 2017 Aug 10;36(32):4573-4584. doi: 10.1038/onc.2017.75. Epub 2017 Apr 3. Oncogene. 2017. PMID: 28368399
Blockade of Stearoyl-CoA-desaturase 1 activity reverts resistance to cisplatin in lung cancer stem cells.
Pisanu ME, Noto A, De Vitis C, Morrone S, Scognamiglio G, Botti G, Venuta F, Diso D, Jakopin Z, Padula F, Ricci A, Mariotta S, Giovagnoli MR, Giarnieri E, Amelio I, Agostini M, Melino G, Ciliberto G, Mancini R. Pisanu ME, et al. Cancer Lett. 2017 Oct 10;406:93-104. doi: 10.1016/j.canlet.2017.07.027. Epub 2017 Aug 7. Cancer Lett. 2017. PMID: 28797843
Inhibition of Stearoyl-CoA desaturase 1 reverts BRAF and MEK inhibition-induced selection of cancer stem cells in BRAF-mutated melanoma.
Pisanu ME, Maugeri-Saccà M, Fattore L, Bruschini S, De Vitis C, Tabbì E, Bellei B, Migliano E, Kovacs D, Camera E, Picardo M, Jakopin Z, Cippitelli C, Bartolazzi A, Raffa S, Torrisi MR, Fulciniti F, Ascierto PA, Ciliberto G, Mancini R. Pisanu ME, et al. J Exp Clin Cancer Res. 2018 Dec 17;37(1):318. doi: 10.1186/s13046-018-0989-7. J Exp Clin Cancer Res. 2018. PMID: 30558661 Free PMC article.
33 results