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[Possibility of iPS cells (discussion)].
Okano H, Yamanaka S, Tsuji S. Okano H, et al. Brain Nerve. 2009 Jun;61(6):711-8. Brain Nerve. 2009. PMID: 19658270 Japanese. No abstract available.
Mitochondrial dysfunction associated with increased oxidative stress and α-synuclein accumulation in PARK2 iPSC-derived neurons and postmortem brain tissue.
Imaizumi Y, Okada Y, Akamatsu W, Koike M, Kuzumaki N, Hayakawa H, Nihira T, Kobayashi T, Ohyama M, Sato S, Takanashi M, Funayama M, Hirayama A, Soga T, Hishiki T, Suematsu M, Yagi T, Ito D, Kosakai A, Hayashi K, Shouji M, Nakanishi A, Suzuki N, Mizuno Y, Mizushima N, Amagai M, Uchiyama Y, Mochizuki H, Hattori N, Okano H. Imaizumi Y, et al. Among authors: okano h. Mol Brain. 2012 Oct 6;5:35. doi: 10.1186/1756-6606-5-35. Mol Brain. 2012. PMID: 23039195 Free PMC article.
Involvement of ER stress in dysmyelination of Pelizaeus-Merzbacher Disease with PLP1 missense mutations shown by iPSC-derived oligodendrocytes.
Numasawa-Kuroiwa Y, Okada Y, Shibata S, Kishi N, Akamatsu W, Shoji M, Nakanishi A, Oyama M, Osaka H, Inoue K, Takahashi K, Yamanaka S, Kosaki K, Takahashi T, Okano H. Numasawa-Kuroiwa Y, et al. Among authors: okano h. Stem Cell Reports. 2014 Apr 24;2(5):648-61. doi: 10.1016/j.stemcr.2014.03.007. eCollection 2014 May 6. Stem Cell Reports. 2014. PMID: 24936452 Free PMC article.
Long-term safety issues of iPSC-based cell therapy in a spinal cord injury model: oncogenic transformation with epithelial-mesenchymal transition.
Nori S, Okada Y, Nishimura S, Sasaki T, Itakura G, Kobayashi Y, Renault-Mihara F, Shimizu A, Koya I, Yoshida R, Kudoh J, Koike M, Uchiyama Y, Ikeda E, Toyama Y, Nakamura M, Okano H. Nori S, et al. Among authors: okano h. Stem Cell Reports. 2015 Mar 10;4(3):360-73. doi: 10.1016/j.stemcr.2015.01.006. Epub 2015 Feb 13. Stem Cell Reports. 2015. PMID: 25684226 Free PMC article.
I2020T mutant LRRK2 iPSC-derived neurons in the Sagamihara family exhibit increased Tau phosphorylation through the AKT/GSK-3β signaling pathway.
Ohta E, Nihira T, Uchino A, Imaizumi Y, Okada Y, Akamatsu W, Takahashi K, Hayakawa H, Nagai M, Ohyama M, Ryo M, Ogino M, Murayama S, Takashima A, Nishiyama K, Mizuno Y, Mochizuki H, Obata F, Okano H. Ohta E, et al. Among authors: okano h. Hum Mol Genet. 2015 Sep 1;24(17):4879-900. doi: 10.1093/hmg/ddv212. Epub 2015 Jun 8. Hum Mol Genet. 2015. PMID: 26056228
1,671 results