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Exploring Selective Inhibition of the First Bromodomain of the Human Bromodomain and Extra-terminal Domain (BET) Proteins.
Raux B, Voitovich Y, Derviaux C, Lugari A, Rebuffet E, Milhas S, Priet S, Roux T, Trinquet E, Guillemot JC, Knapp S, Brunel JM, Fedorov AY, Collette Y, Roche P, Betzi S, Combes S, Morelli X. Raux B, et al. Among authors: roux t. J Med Chem. 2016 Feb 25;59(4):1634-41. doi: 10.1021/acs.jmedchem.5b01708. Epub 2016 Jan 6. J Med Chem. 2016. PMID: 26735842
A Time-Resolved FRET Cell-Based Binding Assay for the Apelin Receptor.
Valencia C, Dujet C, Margathe JF, Iturrioz X, Roux T, Trinquet E, Villa P, Hibert M, Dupuis E, Llorens-Cortes C, Bonnet D. Valencia C, et al. Among authors: roux t. ChemMedChem. 2017 Jun 21;12(12):925-931. doi: 10.1002/cmdc.201700106. Epub 2017 Apr 20. ChemMedChem. 2017. PMID: 28374567
HTRF® Total and Phospho-YAP (Ser127) Cellular Assays.
Zindel D, Vol C, Lecha O, Bequignon I, Bilgic M, Vereecke M, Charrier-Savournin F, Romier M, Trinquet E, Pin JP, Pannequin J, Roux T, Dupuis E, Prézeau L. Zindel D, et al. Among authors: roux t. Methods Mol Biol. 2019;1893:153-166. doi: 10.1007/978-1-4939-8910-2_13. Methods Mol Biol. 2019. PMID: 30565133 Free article.
HTS-compatible FRET-based conformational sensors clarify membrane receptor activation.
Scholler P, Moreno-Delgado D, Lecat-Guillet N, Doumazane E, Monnier C, Charrier-Savournin F, Fabre L, Chouvet C, Soldevila S, Lamarque L, Donsimoni G, Roux T, Zwier JM, Trinquet E, Rondard P, Pin JP. Scholler P, et al. Among authors: roux t. Nat Chem Biol. 2017 Apr;13(4):372-380. doi: 10.1038/nchembio.2286. Epub 2017 Jan 30. Nat Chem Biol. 2017. PMID: 28135236
Protein-Protein Interaction Inhibition (2P2I)-Oriented Chemical Library Accelerates Hit Discovery.
Milhas S, Raux B, Betzi S, Derviaux C, Roche P, Restouin A, Basse MJ, Rebuffet E, Lugari A, Badol M, Kashyap R, Lissitzky JC, Eydoux C, Hamon V, Gourdel ME, Combes S, Zimmermann P, Aurrand-Lions M, Roux T, Rogers C, Müller S, Knapp S, Trinquet E, Collette Y, Guillemot JC, Morelli X. Milhas S, et al. Among authors: roux t. ACS Chem Biol. 2016 Aug 19;11(8):2140-8. doi: 10.1021/acschembio.6b00286. Epub 2016 Jun 3. ACS Chem Biol. 2016. PMID: 27219844
97 results