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Mixed lineage kinase 3 and CD70 cooperation sensitize trastuzumab-resistant HER2+ breast cancer by ceramide-loaded nanoparticles.
Kumar S, Das S, Sun J, Huang Y, Singh SK, Srivastava P, Sondarva G, Nair RS, Viswakarma N, Ganesh BB, Duan L, Maki CG, Hoskins K, Danciu O, Rana B, Li S, Rana A. Kumar S, et al. Among authors: rana a, rana b. Proc Natl Acad Sci U S A. 2022 Sep 20;119(38):e2205454119. doi: 10.1073/pnas.2205454119. Epub 2022 Sep 12. Proc Natl Acad Sci U S A. 2022. PMID: 36095190 Free PMC article.
Mixed lineage kinase 3 inhibition induces T cell activation and cytotoxicity.
Kumar S, Singh SK, Viswakarma N, Sondarva G, Nair RS, Sethupathi P, Sinha SC, Emmadi R, Hoskins K, Danciu O, Thatcher GRJ, Rana B, Rana A. Kumar S, et al. Among authors: rana a, rana b. Proc Natl Acad Sci U S A. 2020 Apr 7;117(14):7961-7970. doi: 10.1073/pnas.1921325117. Epub 2020 Mar 24. Proc Natl Acad Sci U S A. 2020. PMID: 32209667 Free PMC article.
Long-Term Gemcitabine Treatment Reshapes the Pancreatic Tumor Microenvironment and Sensitizes Murine Carcinoma to Combination Immunotherapy.
Principe DR, Narbutis M, Kumar S, Park A, Viswakarma N, Dorman MJ, Kamath SD, Grippo PJ, Fishel ML, Hwang RF, Thummuri D, Underwood PW, Munshi HG, Trevino JG, Rana A. Principe DR, et al. Among authors: rana a. Cancer Res. 2020 Aug 1;80(15):3101-3115. doi: 10.1158/0008-5472.CAN-19-2959. Epub 2020 Apr 1. Cancer Res. 2020. PMID: 32238357 Free PMC article.
XP-524 is a dual-BET/EP300 inhibitor that represses oncogenic KRAS and potentiates immune checkpoint inhibition in pancreatic cancer.
Principe DR, Xiong R, Li Y, Pham TND, Kamath SD, Dubrovskyi O, Ratia K, Huang F, Zhao J, Shen Z, Thummuri D, Daohong Z, Underwood PW, Trevino J, Munshi HG, Thatcher GRJ, Rana A. Principe DR, et al. Among authors: rana a. Proc Natl Acad Sci U S A. 2022 Jan 25;119(4):e2116764119. doi: 10.1073/pnas.2116764119. Proc Natl Acad Sci U S A. 2022. PMID: 35064087 Free PMC article.
Calcium channel blockers potentiate gemcitabine chemotherapy  in pancreatic cancer.
Principe DR, Aissa AF, Kumar S, Pham TND, Underwood PW, Nair R, Ke R, Rana B, Trevino JG, Munshi HG, Benevolenskaya EV, Rana A. Principe DR, et al. Among authors: rana a, rana b. Proc Natl Acad Sci U S A. 2022 May 3;119(18):e2200143119. doi: 10.1073/pnas.2200143119. Epub 2022 Apr 27. Proc Natl Acad Sci U S A. 2022. PMID: 35476525 Free PMC article.
1,406 results