Das S - Search Results

1

Ceftazidime-Avibactam Population Pharmacokinetic Modeling and Pharmacodynamic Target Attainment Across Adult Indications and Patient Subgroups.

Li J, Lovern M, Green ML, Chiu J, Zhou D, Comisar C, Xiong Y, Hing J, MacPherson M, Wright JG, Riccobene T, Carrothers TJ, Das S. Li J, et al. Among authors: das s. Clin Transl Sci. 2019 Mar;12(2):151-163. doi: 10.1111/cts.12585. Epub 2018 Sep 28. Clin Transl Sci. 2019. PMID: 30221827 Free PMC article.

2

Population pharmacokinetic/pharmacodynamic modelling of the anti-TNF-α polyclonal fragment antibody AZD9773 in patients with severe sepsis.

Yates JW, Das S, Mainwaring G, Kemp J. Yates JW, et al. Among authors: das s. J Pharmacokinet Pharmacodyn. 2012 Dec;39(6):591-9. doi: 10.1007/s10928-012-9270-4. Epub 2012 Sep 23. J Pharmacokinet Pharmacodyn. 2012. PMID: 23001587 Clinical Trial.

3

Randomized, placebo-controlled study to assess the impact on QT/QTc interval of supratherapeutic doses of ceftazidime-avibactam or ceftaroline fosamil-avibactam.

Das S, Armstrong J, Mathews D, Li J, Edeki T. Das S, et al. J Clin Pharmacol. 2014 Mar;54(3):331-40. doi: 10.1002/jcph.199. Epub 2013 Oct 22. J Clin Pharmacol. 2014. PMID: 24150927 Clinical Trial.

4

Phase I study assessing the safety, tolerability, and pharmacokinetics of avibactam and ceftazidime-avibactam in healthy Japanese volunteers.

Tominaga N, Edeki T, Li J, Learoyd M, Bouw MR, Das S. Tominaga N, et al. Among authors: das s. J Infect Chemother. 2015 Aug;21(8):551-8. doi: 10.1016/j.jiac.2015.04.006. Epub 2015 Apr 28. J Infect Chemother. 2015. PMID: 26076867 Clinical Trial.

5

Phase 1 study assessing the steady-state concentration of ceftazidime and avibactam in plasma and epithelial lining fluid following two dosing regimens.

Nicolau DP, Siew L, Armstrong J, Li J, Edeki T, Learoyd M, Das S. Nicolau DP, et al. Among authors: das s. J Antimicrob Chemother. 2015 Oct;70(10):2862-9. doi: 10.1093/jac/dkv170. Epub 2015 Jul 1. J Antimicrob Chemother. 2015. PMID: 26133566 Clinical Trial.

6

Randomized pharmacokinetic and drug-drug interaction studies of ceftazidime, avibactam, and metronidazole in healthy subjects.

Das S, Li J, Armstrong J, Learoyd M, Edeki T. Das S, et al. Pharmacol Res Perspect. 2015 Oct;3(5):e00172. doi: 10.1002/prp2.172. Epub 2015 Aug 25. Pharmacol Res Perspect. 2015. PMID: 26516584 Free PMC article.

7

Phase 1 Study Assessing the Pharmacokinetic Profile and Safety of Avibactam in Patients With Renal Impairment.

Merdjan H, Tarral A, Das S, Li J. Merdjan H, et al. Among authors: das s. J Clin Pharmacol. 2017 Feb;57(2):211-218. doi: 10.1002/jcph.793. Epub 2016 Sep 27. J Clin Pharmacol. 2017. PMID: 27402250 Clinical Trial.

8

Phase I Study Assessing the Pharmacokinetic Profile, Safety, and Tolerability of a Single Dose of Ceftazidime-Avibactam in Hospitalized Pediatric Patients.

Bradley JS, Armstrong J, Arrieta A, Bishai R, Das S, Delair S, Edeki T, Holmes WC, Li J, Moffett KS, Mukundan D, Perez N, Romero JR, Speicher D, Sullivan JE, Zhou D. Bradley JS, et al. Among authors: das s. Antimicrob Agents Chemother. 2016 Sep 23;60(10):6252-9. doi: 10.1128/AAC.00862-16. Print 2016 Oct. Antimicrob Agents Chemother. 2016. PMID: 27503642 Free PMC article. Clinical Trial.

9

Population PK Modeling and Target Attainment Simulations to Support Dosing of Ceftaroline Fosamil in Pediatric Patients With Acute Bacterial Skin and Skin Structure Infections and Community-Acquired Bacterial Pneumonia.

Riccobene TA, Khariton T, Knebel W, Das S, Li J, Jandourek A, Carrothers TJ, Bradley JS. Riccobene TA, et al. Among authors: das s. J Clin Pharmacol. 2017 Mar;57(3):345-355. doi: 10.1002/jcph.809. Epub 2016 Sep 27. J Clin Pharmacol. 2017. PMID: 27510635

10

Avibactam Pharmacokinetic/Pharmacodynamic Targets.

Nichols WW, Newell P, Critchley IA, Riccobene T, Das S. Nichols WW, et al. Among authors: das s. Antimicrob Agents Chemother. 2018 May 25;62(6):e02446-17. doi: 10.1128/AAC.02446-17. Print 2018 Jun. Antimicrob Agents Chemother. 2018. PMID: 29610208 Free PMC article. Review.

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