Brummelkamp TR - Search Results

1

Nedd4-Binding Protein 1 and TNFAIP3-Interacting Protein 1 Control MHC-1 Display in Neuroblastoma.

Spel L, Nieuwenhuis J, Haarsma R, Stickel E, Bleijerveld OB, Altelaar M, Boelens JJ, Brummelkamp TR, Nierkens S, Boes M. Spel L, et al. Among authors: brummelkamp tr. Cancer Res. 2018 Dec 1;78(23):6621-6631. doi: 10.1158/0008-5472.CAN-18-0545. Epub 2018 Sep 13. Cancer Res. 2018. PMID: 30213788

2

USP9X downregulation renders breast cancer cells resistant to tamoxifen.

Oosterkamp HM, Hijmans EM, Brummelkamp TR, Canisius S, Wessels LF, Zwart W, Bernards R. Oosterkamp HM, et al. Among authors: brummelkamp tr. Cancer Res. 2014 Jul 15;74(14):3810-20. doi: 10.1158/0008-5472.CAN-13-1960. Cancer Res. 2014. PMID: 25028367

3

Genome-Wide Identification and Characterization of Novel Factors Conferring Resistance to Topoisomerase II Poisons in Cancer.

Wijdeven RH, Pang B, van der Zanden SY, Qiao X, Blomen V, Hoogstraat M, Lips EH, Janssen L, Wessels L, Brummelkamp TR, Neefjes J. Wijdeven RH, et al. Among authors: brummelkamp tr. Cancer Res. 2015 Oct 1;75(19):4176-87. doi: 10.1158/0008-5472.CAN-15-0380. Epub 2015 Aug 10. Cancer Res. 2015. PMID: 26260527

4

Gene essentiality and synthetic lethality in haploid human cells.

Blomen VA, Májek P, Jae LT, Bigenzahn JW, Nieuwenhuis J, Staring J, Sacco R, van Diemen FR, Olk N, Stukalov A, Marceau C, Janssen H, Carette JE, Bennett KL, Colinge J, Superti-Furga G, Brummelkamp TR. Blomen VA, et al. Among authors: brummelkamp tr. Science. 2015 Nov 27;350(6264):1092-6. doi: 10.1126/science.aac7557. Epub 2015 Oct 15. Science. 2015. PMID: 26472760

5

PLA2G16 represents a switch between entry and clearance of Picornaviridae.

Staring J, von Castelmur E, Blomen VA, van den Hengel LG, Brockmann M, Baggen J, Thibaut HJ, Nieuwenhuis J, Janssen H, van Kuppeveld FJ, Perrakis A, Carette JE, Brummelkamp TR. Staring J, et al. Among authors: brummelkamp tr. Nature. 2017 Jan 19;541(7637):412-416. doi: 10.1038/nature21032. Epub 2017 Jan 11. Nature. 2017. PMID: 28077878

6

Genetic wiring maps of single-cell protein states reveal an off-switch for GPCR signalling.

Brockmann M, Blomen VA, Nieuwenhuis J, Stickel E, Raaben M, Bleijerveld OB, Altelaar AFM, Jae LT, Brummelkamp TR. Brockmann M, et al. Among authors: brummelkamp tr. Nature. 2017 Jun 8;546(7657):307-311. doi: 10.1038/nature22376. Epub 2017 May 31. Nature. 2017. PMID: 28562590

7

Haploid Mammalian Genetic Screen Identifies UBXD8 as a Key Determinant of HMGCR Degradation and Cholesterol Biosynthesis.

Loregger A, Raaben M, Tan J, Scheij S, Moeton M, van den Berg M, Gelberg-Etel H, Stickel E, Roitelman J, Brummelkamp T, Zelcer N. Loregger A, et al. Arterioscler Thromb Vasc Biol. 2017 Nov;37(11):2064-2074. doi: 10.1161/ATVBAHA.117.310002. Epub 2017 Sep 7. Arterioscler Thromb Vasc Biol. 2017. PMID: 28882874 Free PMC article.

8

Vasohibins encode tubulin detyrosinating activity.

Nieuwenhuis J, Adamopoulos A, Bleijerveld OB, Mazouzi A, Stickel E, Celie P, Altelaar M, Knipscheer P, Perrakis A, Blomen VA, Brummelkamp TR. Nieuwenhuis J, et al. Among authors: brummelkamp tr. Science. 2017 Dec 15;358(6369):1453-1456. doi: 10.1126/science.aao5676. Epub 2017 Nov 16. Science. 2017. PMID: 29146869

9

Haploid genetic screens identify genetic vulnerabilities to microtubule-targeting agents.

Gerhards NM, Blomen VA, Mutlu M, Nieuwenhuis J, Howald D, Guyader C, Jonkers J, Brummelkamp TR, Rottenberg S. Gerhards NM, et al. Among authors: brummelkamp tr. Mol Oncol. 2018 Jun;12(6):953-971. doi: 10.1002/1878-0261.12307. Epub 2018 May 1. Mol Oncol. 2018. PMID: 29689640 Free PMC article.

10

The Tubulin Detyrosination Cycle: Function and Enzymes.

Nieuwenhuis J, Brummelkamp TR. Nieuwenhuis J, et al. Among authors: brummelkamp tr. Trends Cell Biol. 2019 Jan;29(1):80-92. doi: 10.1016/j.tcb.2018.08.003. Epub 2018 Sep 10. Trends Cell Biol. 2019. PMID: 30213517 Review.

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