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Depsipeptides Featuring a Neutral P1 Are Potent Inhibitors of Kallikrein-Related Peptidase 6 with On-Target Cellular Activity.
J Med Chem. 2018 Oct 11;61(19):8859-8874. doi: 10.1021/acs.jmedchem.8b01106. Epub 2018 Sep 28.
J Med Chem. 2018.
PMID: 30212625
Practical synthesis of a phthalimide-based Cereblon ligand to enable PROTAC development.
Lohbeck J, Miller AK.
Lohbeck J, et al.
Bioorg Med Chem Lett. 2016 Nov 1;26(21):5260-5262. doi: 10.1016/j.bmcl.2016.09.048. Epub 2016 Sep 19.
Bioorg Med Chem Lett. 2016.
PMID: 27687673
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Scalable synthesis and structural characterization of reversible KLK6 inhibitors.
Baumann A, Isak D, Lohbeck J, Jagtap PKA, Hennig J, Miller AK.
Baumann A, et al. Among authors: lohbeck j.
RSC Adv. 2022 Sep 21;12(41):26989-26993. doi: 10.1039/d2ra04670a. eCollection 2022 Sep 16.
RSC Adv. 2022.
PMID: 36320846
Free PMC article.
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Correction: Scalable synthesis and structural characterization of reversible KLK6 inhibitors.
Baumann A, Isak D, Lohbeck J, Jagtap PKA, Hennig J, Miller AK.
Baumann A, et al. Among authors: lohbeck j.
RSC Adv. 2022 Oct 10;12(44):28677. doi: 10.1039/d2ra90102a. eCollection 2022 Oct 4.
RSC Adv. 2022.
PMID: 36321863
Free PMC article.
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Competition for cysteine acylation by C16:0 and C18:0 derived lipids is a global phenomenon in the proteome.
Nůsková H, Cortizo FG, Schwenker LS, Sachsenheimer T, Diakonov EE, Tiebe M, Schneider M, Lohbeck J, Reid C, Kopp-Schneider A, Helm D, Brügger B, Miller AK, Teleman AA.
Nůsková H, et al. Among authors: lohbeck j.
J Biol Chem. 2023 Sep;299(9):105088. doi: 10.1016/j.jbc.2023.105088. Epub 2023 Jul 24.
J Biol Chem. 2023.
PMID: 37495107
Free PMC article.
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