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The Hippo pathway effector TAZ induces TEAD-dependent liver inflammation and tumors.
Hagenbeek TJ, Webster JD, Kljavin NM, Chang MT, Pham T, Lee HJ, Klijn C, Cai AG, Totpal K, Ravishankar B, Yang N, Lee DH, Walsh KB, Hatzivassiliou G, de la Cruz CC, Gould SE, Wu X, Lee WP, Yang S, Zhang Z, Gu Q, Ji Q, Jackson EL, Lim DS, Dey A. Hagenbeek TJ, et al. Among authors: lee dh, lee wp, lee hj. Sci Signal. 2018 Sep 11;11(547):eaaj1757. doi: 10.1126/scisignal.aaj1757. Sci Signal. 2018. PMID: 30206136
AK2 is an AMP-sensing negative regulator of BRAF in tumorigenesis.
Kim H, Jeong M, Na DH, Ryu SH, Jeong EI, Jung K, Kang J, Lee HJ, Sim T, Yu DY, Yu HC, Cho BH, Jung YK. Kim H, et al. Among authors: lee hj. Cell Death Dis. 2022 May 18;13(5):469. doi: 10.1038/s41419-022-04921-7. Cell Death Dis. 2022. PMID: 35585049 Free PMC article.
Noncovalent wild-type-sparing inhibitors of EGFR T790M.
Lee HJ, Schaefer G, Heffron TP, Shao L, Ye X, Sideris S, Malek S, Chan E, Merchant M, La H, Ubhayakar S, Yauch RL, Pirazzoli V, Politi K, Settleman J. Lee HJ, et al. Cancer Discov. 2013 Feb;3(2):168-81. doi: 10.1158/2159-8290.CD-12-0357. Epub 2012 Dec 10. Cancer Discov. 2013. PMID: 23229345 Free PMC article.
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