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Ure(k)a! Sirtuins Regulate Mitochondria.
Hallows WC, Smith BC, Lee S, Denu JM. Hallows WC, et al. Among authors: denu jm. Cell. 2009 May 1;137(3):404-6. doi: 10.1016/j.cell.2009.04.036. Cell. 2009. PMID: 19410538 Free PMC article.
Sirt3 promotes the urea cycle and fatty acid oxidation during dietary restriction.
Hallows WC, Yu W, Smith BC, Devries MK, Ellinger JJ, Someya S, Shortreed MR, Prolla T, Markley JL, Smith LM, Zhao S, Guan KL, Denu JM. Hallows WC, et al. Among authors: denu jm. Mol Cell. 2011 Jan 21;41(2):139-49. doi: 10.1016/j.molcel.2011.01.002. Mol Cell. 2011. PMID: 21255725 Free PMC article.
The deacetylase Sirt6 activates the acetyltransferase GCN5 and suppresses hepatic gluconeogenesis.
Dominy JE Jr, Lee Y, Jedrychowski MP, Chim H, Jurczak MJ, Camporez JP, Ruan HB, Feldman J, Pierce K, Mostoslavsky R, Denu JM, Clish CB, Yang X, Shulman GI, Gygi SP, Puigserver P. Dominy JE Jr, et al. Among authors: denu jm. Mol Cell. 2012 Dec 28;48(6):900-13. doi: 10.1016/j.molcel.2012.09.030. Epub 2012 Nov 8. Mol Cell. 2012. PMID: 23142079 Free PMC article.
Calorie restriction and SIRT3 trigger global reprogramming of the mitochondrial protein acetylome.
Hebert AS, Dittenhafer-Reed KE, Yu W, Bailey DJ, Selen ES, Boersma MD, Carson JJ, Tonelli M, Balloon AJ, Higbee AJ, Westphall MS, Pagliarini DJ, Prolla TA, Assadi-Porter F, Roy S, Denu JM, Coon JJ. Hebert AS, et al. Among authors: denu jm. Mol Cell. 2013 Jan 10;49(1):186-99. doi: 10.1016/j.molcel.2012.10.024. Epub 2012 Nov 29. Mol Cell. 2013. PMID: 23201123 Free PMC article.
Stoichiometry of site-specific lysine acetylation in an entire proteome.
Baeza J, Dowell JA, Smallegan MJ, Fan J, Amador-Noguez D, Khan Z, Denu JM. Baeza J, et al. Among authors: denu jm. J Biol Chem. 2014 Aug 1;289(31):21326-38. doi: 10.1074/jbc.M114.581843. Epub 2014 Jun 10. J Biol Chem. 2014. PMID: 24917678 Free PMC article.
204 results