A P450 BM-3 mutant hydroxylates alkanes, cycloalkanes, arenes and heteroarenes.
Appel D, Lutz-Wahl S, Fischer P, Schwaneberg U, Schmid RD.
Appel D, et al. Among authors: schwaneberg u.
J Biotechnol. 2001 Jun 15;88(2):167-71. doi: 10.1016/s0168-1656(01)00249-8.
J Biotechnol. 2001.
PMID: 11403851
For native P450 BM-3, no other substrates than fatty acids or an indolyl-fatty acid derivative have been reported (Li, Q.S., Schwaneberg, U., Fischer, P., Schmid, R.D., 2000. Directed evolution of the fatty-acid hydroxylase P450BM-3 into an indole-hydroxylating cata …
For native P450 BM-3, no other substrates than fatty acids or an indolyl-fatty acid derivative have been reported (Li, Q.S., Schwaneberg …