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Pharmacokinetics, Safety, and Efficacy of an Allometric Miltefosine Regimen for the Treatment of Visceral Leishmaniasis in Eastern African Children: An Open-label, Phase II Clinical Trial.
Mbui J, Olobo J, Omollo R, Solomos A, Kip AE, Kirigi G, Sagaki P, Kimutai R, Were L, Omollo T, Egondi TW, Wasunna M, Alvar J, Dorlo TPC, Alves F. Mbui J, et al. Among authors: kirigi g. Clin Infect Dis. 2019 Apr 24;68(9):1530-1538. doi: 10.1093/cid/ciy747. Clin Infect Dis. 2019. PMID: 30188978 Free PMC article. Clinical Trial.
Safety and efficacy of miltefosine alone and in combination with sodium stibogluconate and liposomal amphotericin B for the treatment of primary visceral leishmaniasis in East Africa: study protocol for a randomized controlled trial.
Omollo R, Alexander N, Edwards T, Khalil EA, Younis BM, Abuzaid AA, Wasunna M, Njoroge N, Kinoti D, Kirigi G, Dorlo TP, Ellis S, Balasegaram M, Musa AM. Omollo R, et al. Among authors: kirigi g. Trials. 2011 Jun 30;12:166. doi: 10.1186/1745-6215-12-166. Trials. 2011. PMID: 21718522 Free PMC article. Clinical Trial.
Efficacy and Safety of AmBisome in Combination with Sodium Stibogluconate or Miltefosine and Miltefosine Monotherapy for African Visceral Leishmaniasis: Phase II Randomized Trial.
Wasunna M, Njenga S, Balasegaram M, Alexander N, Omollo R, Edwards T, Dorlo TP, Musa B, Ali MH, Elamin MY, Kirigi G, Juma R, Kip AE, Schoone GJ, Hailu A, Olobo J, Ellis S, Kimutai R, Wells S, Khalil EA, Strub Wourgaft N, Alves F, Musa A. Wasunna M, et al. Among authors: kirigi g. PLoS Negl Trop Dis. 2016 Sep 14;10(9):e0004880. doi: 10.1371/journal.pntd.0004880. eCollection 2016 Sep. PLoS Negl Trop Dis. 2016. PMID: 27627654 Free PMC article. Clinical Trial.
Visceral leishmaniasis relapse hazard is linked to reduced miltefosine exposure in patients from Eastern Africa: a population pharmacokinetic/pharmacodynamic study.
Dorlo TPC, Kip AE, Younis BM, Ellis SJ, Alves F, Beijnen JH, Njenga S, Kirigi G, Hailu A, Olobo J, Musa AM, Balasegaram M, Wasunna M, Karlsson MO, Khalil EAG. Dorlo TPC, et al. Among authors: kirigi g. J Antimicrob Chemother. 2017 Nov 1;72(11):3131-3140. doi: 10.1093/jac/dkx283. J Antimicrob Chemother. 2017. PMID: 28961737 Free PMC article. Clinical Trial.
Sodium stibogluconate (SSG) & paromomycin combination compared to SSG for visceral leishmaniasis in East Africa: a randomised controlled trial.
Musa A, Khalil E, Hailu A, Olobo J, Balasegaram M, Omollo R, Edwards T, Rashid J, Mbui J, Musa B, Abuzaid AA, Ahmed O, Fadlalla A, El-Hassan A, Mueller M, Mucee G, Njoroge S, Manduku V, Mutuma G, Apadet L, Lodenyo H, Mutea D, Kirigi G, Yifru S, Mengistu G, Hurissa Z, Hailu W, Weldegebreal T, Tafes H, Mekonnen Y, Makonnen E, Ndegwa S, Sagaki P, Kimutai R, Kesusu J, Owiti R, Ellis S, Wasunna M. Musa A, et al. Among authors: kirigi g. PLoS Negl Trop Dis. 2012;6(6):e1674. doi: 10.1371/journal.pntd.0001674. Epub 2012 Jun 19. PLoS Negl Trop Dis. 2012. PMID: 22724029 Free PMC article. Clinical Trial.
Validation of two rapid diagnostic tests for visceral leishmaniasis in Kenya.
Mbui J, Wasunna M, Balasegaram M, Laussermayer A, Juma R, Njenga SN, Kirigi G, Riongoita M, de la Tour R, van Peteghem J, Omollo R, Chappuis F. Mbui J, et al. Among authors: kirigi g. PLoS Negl Trop Dis. 2013 Sep 26;7(9):e2441. doi: 10.1371/journal.pntd.0002441. eCollection 2013. PLoS Negl Trop Dis. 2013. PMID: 24086782 Free PMC article.
24 results