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Involvement of Innate and Adaptive Immune Systems Alterations in the Pathophysiology and Treatment of Depression.
Front Neurosci. 2018 Aug 17;12:547. doi: 10.3389/fnins.2018.00547. eCollection 2018.
Front Neurosci. 2018.
PMID: 30174579
Free PMC article.
Review.
Inflammatory and neurodegenerative pathophysiology implicated in postpartum depression.
Worthen RJ, Beurel E.
Worthen RJ, et al.
Neurobiol Dis. 2022 Apr;165:105646. doi: 10.1016/j.nbd.2022.105646. Epub 2022 Jan 29.
Neurobiol Dis. 2022.
PMID: 35104645
Free PMC article.
Review.
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Anti-inflammatory IL-10 administration rescues depression-associated learning and memory deficits in mice.
Worthen RJ, Garzon Zighelboim SS, Torres Jaramillo CS, Beurel E.
Worthen RJ, et al.
J Neuroinflammation. 2020 Aug 22;17(1):246. doi: 10.1186/s12974-020-01922-1.
J Neuroinflammation. 2020.
PMID: 32828124
Free PMC article.
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Insulin growth factor 2 (IGF2) as an emergent target in psychiatric and neurological disorders. Review.
Pardo M, Cheng Y, Sitbon YH, Lowell JA, Grieco SF, Worthen RJ, Desse S, Barreda-Diaz A.
Pardo M, et al. Among authors: worthen rj.
Neurosci Res. 2019 Dec;149:1-13. doi: 10.1016/j.neures.2018.10.012. Epub 2018 Oct 31.
Neurosci Res. 2019.
PMID: 30389571
Review.
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Stressed and Inflamed, Can GSK3 Be Blamed?
Jope RS, Cheng Y, Lowell JA, Worthen RJ, Sitbon YH, Beurel E.
Jope RS, et al. Among authors: worthen rj.
Trends Biochem Sci. 2017 Mar;42(3):180-192. doi: 10.1016/j.tibs.2016.10.009. Epub 2016 Nov 19.
Trends Biochem Sci. 2017.
PMID: 27876551
Free PMC article.
Review.
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TNFα disrupts blood brain barrier integrity to maintain prolonged depressive-like behavior in mice.
Cheng Y, Desse S, Martinez A, Worthen RJ, Jope RS, Beurel E.
Cheng Y, et al. Among authors: worthen rj.
Brain Behav Immun. 2018 Mar;69:556-567. doi: 10.1016/j.bbi.2018.02.003. Epub 2018 Feb 13.
Brain Behav Immun. 2018.
PMID: 29452218
Free PMC article.
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Altered metabolism and persistent starvation behaviors caused by reduced AMPK function in Drosophila.
Johnson EC, Kazgan N, Bretz CA, Forsberg LJ, Hector CE, Worthen RJ, Onyenwoke R, Brenman JE.
Johnson EC, et al. Among authors: worthen rj.
PLoS One. 2010 Sep 20;5(9):e12799. doi: 10.1371/journal.pone.0012799.
PLoS One. 2010.
PMID: 20862213
Free PMC article.
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The actin-binding protein capulet genetically interacts with the microtubule motor kinesin to maintain neuronal dendrite homeostasis.
Medina PM, Worthen RJ, Forsberg LJ, Brenman JE.
Medina PM, et al. Among authors: worthen rj.
PLoS One. 2008 Aug 25;3(8):e3054. doi: 10.1371/journal.pone.0003054.
PLoS One. 2008.
PMID: 18725959
Free PMC article.
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