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Daily Onset of Light and Darkness Differentially Controls Hematopoietic Stem Cell Differentiation and Maintenance.
Golan K, Kumari A, Kollet O, Khatib-Massalha E, Subramaniam MD, Ferreira ZS, Avemaria F, Rzeszotek S, García-García A, Xie S, Flores-Figueroa E, Gur-Cohen S, Itkin T, Ludin-Tal A, Massalha H, Bernshtein B, Ciechanowicz AK, Brandis A, Mehlman T, Bhattacharya S, Bertagna M, Cheng H, Petrovich-Kopitman E, Janus T, Kaushansky N, Cheng T, Sagi I, Ratajczak MZ, Méndez-Ferrer S, Dick JE, Markus RP, Lapidot T. Golan K, et al. Among authors: kaushansky n. Cell Stem Cell. 2018 Oct 4;23(4):572-585.e7. doi: 10.1016/j.stem.2018.08.002. Epub 2018 Aug 30. Cell Stem Cell. 2018. PMID: 30174297 Free article.
Targeting SRSF2 mutations in leukemia with RKI-1447: A strategy to impair cellular division and nuclear structure.
Su M, Fleischer T, Grosheva I, Horev MB, Olszewska M, Mattioli CC, Barr H, Plotnikov A, Carvalho S, Moskovich Y, Minden MD, Chapal-Ilani N, Wainstein A, Papapetrou EP, Dezorella N, Cheng T, Kaushansky N, Geiger B, Shlush LI. Su M, et al. Among authors: kaushansky n. iScience. 2024 Mar 6;27(4):109443. doi: 10.1016/j.isci.2024.109443. eCollection 2024 Apr 19. iScience. 2024. PMID: 38558935 Free PMC article.
Small Molecules Co-targeting CKIα and the Transcriptional Kinases CDK7/9 Control AML in Preclinical Models.
Minzel W, Venkatachalam A, Fink A, Hung E, Brachya G, Burstain I, Shaham M, Rivlin A, Omer I, Zinger A, Elias S, Winter E, Erdman PE, Sullivan RW, Fung L, Mercurio F, Li D, Vacca J, Kaushansky N, Shlush L, Oren M, Levine R, Pikarsky E, Snir-Alkalay I, Ben-Neriah Y. Minzel W, et al. Among authors: kaushansky n. Cell. 2018 Sep 20;175(1):171-185.e25. doi: 10.1016/j.cell.2018.07.045. Epub 2018 Aug 23. Cell. 2018. PMID: 30146162 Free PMC article.
An improved molecular inversion probe based targeted sequencing approach for low variant allele frequency.
Biezuner T, Brilon Y, Arye AB, Oron B, Kadam A, Danin A, Furer N, Minden MD, Hwan Kim DD, Shapira S, Arber N, Dick J, Thavendiranathan P, Moskovitz Y, Kaushansky N, Chapal-Ilani N, Shlush LI. Biezuner T, et al. Among authors: kaushansky n. NAR Genom Bioinform. 2022 Feb 8;4(1):lqab125. doi: 10.1093/nargab/lqab125. eCollection 2022 Mar. NAR Genom Bioinform. 2022. PMID: 35156021 Free PMC article.
Inflammatory signals from fatty bone marrow support DNMT3A driven clonal hematopoiesis.
Zioni N, Bercovich AA, Chapal-Ilani N, Bacharach T, Rappoport N, Solomon A, Avraham R, Kopitman E, Porat Z, Sacma M, Hartmut G, Scheller M, Muller-Tidow C, Lipka D, Shlush E, Minden M, Kaushansky N, Shlush LI. Zioni N, et al. Among authors: kaushansky n. Nat Commun. 2023 Apr 12;14(1):2070. doi: 10.1038/s41467-023-36906-1. Nat Commun. 2023. PMID: 37045808 Free PMC article.
Pseudo-mutant P53 is a unique phenotype of DNMT3A-mutated pre-leukemia.
Tuval A, Brilon Y, Azogy H, Moskovitz Y, Leshkowitz D, Salame TM, Minden MD, Tal P, Rotter V, Oren M, Kaushansky N, Shlush LI. Tuval A, et al. Among authors: kaushansky n. Haematologica. 2022 Nov 1;107(11):2548-2561. doi: 10.3324/haematol.2021.280329. Haematologica. 2022. PMID: 35199506 Free PMC article.
42 results