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Aβ1-42 monomers or oligomers have different effects on autophagy and apoptosis.
Guglielmotto M, Monteleone D, Piras A, Valsecchi V, Tropiano M, Ariano S, Fornaro M, Vercelli A, Puyal J, Arancio O, Tabaton M, Tamagno E. Guglielmotto M, et al. Among authors: arancio o. Autophagy. 2014 Oct 1;10(10):1827-43. doi: 10.4161/auto.30001. Epub 2014 Aug 12. Autophagy. 2014. PMID: 25136804 Free PMC article.
Loss of mTOR-dependent macroautophagy causes autistic-like synaptic pruning deficits.
Tang G, Gudsnuk K, Kuo SH, Cotrina ML, Rosoklija G, Sosunov A, Sonders MS, Kanter E, Castagna C, Yamamoto A, Yue Z, Arancio O, Peterson BS, Champagne F, Dwork AJ, Goldman J, Sulzer D. Tang G, et al. Among authors: arancio o. Neuron. 2014 Sep 3;83(5):1131-43. doi: 10.1016/j.neuron.2014.07.040. Epub 2014 Aug 21. Neuron. 2014. PMID: 25155956 Free PMC article.
Alpha-synuclein: between synaptic function and dysfunction.
Di Rosa G, Puzzo D, Sant'Angelo A, Trinchese F, Arancio O. Di Rosa G, et al. Among authors: arancio o. Histol Histopathol. 2003 Oct;18(4):1257-66. doi: 10.14670/HH-18.1257. Histol Histopathol. 2003. PMID: 12973692 Review.
Inhibition of amyloid-beta (Abeta) peptide-binding alcohol dehydrogenase-Abeta interaction reduces Abeta accumulation and improves mitochondrial function in a mouse model of Alzheimer's disease.
Yao J, Du H, Yan S, Fang F, Wang C, Lue LF, Guo L, Chen D, Stern DM, Gunn Moore FJ, Xi Chen J, Arancio O, Yan SS. Yao J, et al. Among authors: arancio o. J Neurosci. 2011 Feb 9;31(6):2313-20. doi: 10.1523/JNEUROSCI.4717-10.2011. J Neurosci. 2011. PMID: 21307267 Free PMC article.
ABAD directly links Abeta to mitochondrial toxicity in Alzheimer's disease.
Lustbader JW, Cirilli M, Lin C, Xu HW, Takuma K, Wang N, Caspersen C, Chen X, Pollak S, Chaney M, Trinchese F, Liu S, Gunn-Moore F, Lue LF, Walker DG, Kuppusamy P, Zewier ZL, Arancio O, Stern D, Yan SS, Wu H. Lustbader JW, et al. Among authors: arancio o. Science. 2004 Apr 16;304(5669):448-52. doi: 10.1126/science.1091230. Science. 2004. PMID: 15087549
206 results