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Human AML activates the aryl hydrocarbon receptor pathway to impair NK cell development and function.
Scoville SD, Nalin AP, Chen L, Chen L, Zhang MH, McConnell K, Beceiro Casas S, Ernst G, Traboulsi AA, Hashi N, Williams M, Zhang X, Hughes T, Mishra A, Benson DM, Saultz JN, Yu J, Freud AG, Caligiuri MA, Mundy-Bosse BL. Scoville SD, et al. Among authors: benson dm. Blood. 2018 Oct 25;132(17):1792-1804. doi: 10.1182/blood-2018-03-838474. Epub 2018 Aug 29. Blood. 2018. PMID: 30158248 Free PMC article.
Pro- and antiinflammatory cytokine signaling: reciprocal antagonism regulates interferon-gamma production by human natural killer cells.
Yu J, Wei M, Becknell B, Trotta R, Liu S, Boyd Z, Jaung MS, Blaser BW, Sun J, Benson DM Jr, Mao H, Yokohama A, Bhatt D, Shen L, Davuluri R, Weinstein M, Marcucci G, Caligiuri MA. Yu J, et al. Among authors: benson dm jr. Immunity. 2006 May;24(5):575-90. doi: 10.1016/j.immuni.2006.03.016. Immunity. 2006. PMID: 16713975 Free article.
Hlx homeobox transcription factor negatively regulates interferon-gamma production in monokine-activated natural killer cells.
Becknell B, Hughes TL, Freud AG, Blaser BW, Yu J, Trotta R, Mao HC, Caligiuri de Jesús ML, Alghothani M, Benson DM Jr, Lehman A, Jarjoura D, Perrotti D, Bates MD, Caligiuri MA. Becknell B, et al. Among authors: benson dm jr. Blood. 2007 Mar 15;109(6):2481-7. doi: 10.1182/blood-2006-10-050096. Epub 2006 Nov 16. Blood. 2007. PMID: 17110450 Free PMC article.
Preclinical characterization of 1-7F9, a novel human anti-KIR receptor therapeutic antibody that augments natural killer-mediated killing of tumor cells.
Romagné F, André P, Spee P, Zahn S, Anfossi N, Gauthier L, Capanni M, Ruggeri L, Benson DM Jr, Blaser BW, Della Chiesa M, Moretta A, Vivier E, Caligiuri MA, Velardi A, Wagtmann N. Romagné F, et al. Among authors: benson dm jr. Blood. 2009 Sep 24;114(13):2667-77. doi: 10.1182/blood-2009-02-206532. Epub 2009 Jun 24. Blood. 2009. PMID: 19553639 Free PMC article.
CD94 defines phenotypically and functionally distinct mouse NK cell subsets.
Yu J, Wei M, Mao H, Zhang J, Hughes T, Mitsui T, Park IK, Hwang C, Liu S, Marcucci G, Trotta R, Benson DM Jr, Caligiuri MA. Yu J, et al. Among authors: benson dm jr. J Immunol. 2009 Oct 15;183(8):4968-74. doi: 10.4049/jimmunol.0900907. J Immunol. 2009. PMID: 19801519 Free PMC article.
CD19 targeting of chronic lymphocytic leukemia with a novel Fc-domain-engineered monoclonal antibody.
Awan FT, Lapalombella R, Trotta R, Butchar JP, Yu B, Benson DM Jr, Roda JM, Cheney C, Mo X, Lehman A, Jones J, Flynn J, Jarjoura D, Desjarlais JR, Tridandapani S, Caligiuri MA, Muthusamy N, Byrd JC. Awan FT, et al. Among authors: benson dm jr. Blood. 2010 Feb 11;115(6):1204-13. doi: 10.1182/blood-2009-06-229039. Epub 2009 Dec 2. Blood. 2010. PMID: 19965644 Free PMC article.
The PD-1/PD-L1 axis modulates the natural killer cell versus multiple myeloma effect: a therapeutic target for CT-011, a novel monoclonal anti-PD-1 antibody.
Benson DM Jr, Bakan CE, Mishra A, Hofmeister CC, Efebera Y, Becknell B, Baiocchi RA, Zhang J, Yu J, Smith MK, Greenfield CN, Porcu P, Devine SM, Rotem-Yehudar R, Lozanski G, Byrd JC, Caligiuri MA. Benson DM Jr, et al. Blood. 2010 Sep 30;116(13):2286-94. doi: 10.1182/blood-2010-02-271874. Epub 2010 May 11. Blood. 2010. PMID: 20460501 Free PMC article.
NKp46 identifies an NKT cell subset susceptible to leukemic transformation in mouse and human.
Yu J, Mitsui T, Wei M, Mao H, Butchar JP, Shah MV, Zhang J, Mishra A, Alvarez-Breckenridge C, Liu X, Liu S, Yokohama A, Trotta R, Marcucci G Jr, Benson DM, Loughran TP Jr, Tridandapani S, Caligiuri MA. Yu J, et al. Among authors: benson dm. J Clin Invest. 2011 Apr;121(4):1456-70. doi: 10.1172/JCI43242. J Clin Invest. 2011. PMID: 21364281 Free PMC article.
223 results