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Intestinal TGR5 agonism improves hepatic steatosis and insulin sensitivity in Western diet-fed mice.
Am J Physiol Gastrointest Liver Physiol. 2019 Mar 1;316(3):G412-G424. doi: 10.1152/ajpgi.00300.2018. Epub 2019 Jan 3.
Am J Physiol Gastrointest Liver Physiol. 2019.
PMID: 30605011
Free PMC article.
Inhibition of sodium/hydrogen exchanger 3 in the gastrointestinal tract by tenapanor reduces paracellular phosphate permeability.
King AJ, Siegel M, He Y, Nie B, Wang J, Koo-McCoy S, Minassian NA, Jafri Q, Pan D, Kohler J, Kumaraswamy P, Kozuka K, Lewis JG, Dragoli D, Rosenbaum DP, O'Neill D, Plain A, Greasley PJ, Jönsson-Rylander AC, Karlsson D, Behrendt M, Strömstedt M, Ryden-Bergsten T, Knöpfel T, Pastor Arroyo EM, Hernando N, Marks J, Donowitz M, Wagner CA, Alexander RT, Caldwell JS.
King AJ, et al. Among authors: dragoli d.
Sci Transl Med. 2018 Aug 29;10(456):eaam6474. doi: 10.1126/scitranslmed.aam6474.
Sci Transl Med. 2018.
PMID: 30158152
Free PMC article.
Clinical Trial.
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Chiral N-Acyl-tert-butanesulfinamides: The "Safety-Catch" Principle Applied to Diastereoselective Enolate Alkylations.
Backes BJ, Dragoli DR, Ellman JA.
Backes BJ, et al. Among authors: dragoli dr.
J Org Chem. 1999 Jul 23;64(15):5472-5478. doi: 10.1021/jo990271w.
J Org Chem. 1999.
PMID: 11674609
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Design, synthesis, and utility of a support-bound tert-butanesulfinamide.
Dragoli DR, Burdett MT, Ellman JA.
Dragoli DR, et al.
J Am Chem Soc. 2001 Oct 17;123(41):10127-8. doi: 10.1021/ja016349j.
J Am Chem Soc. 2001.
PMID: 11592904
No abstract available.
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Parallel synthesis of prostaglandin E1 analogues.
Dragoli DR, Thompson LA, O'Brien J, Ellman JA.
Dragoli DR, et al.
J Comb Chem. 1999 Nov-Dec;1(6):534-9. doi: 10.1021/cc990033e.
J Comb Chem. 1999.
PMID: 10748730
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