LNX1 contributes to tumor growth by down-regulating p53 stability.
Park R, Kim H, Jang M, Jo D, Park YI, Namkoong S, Lee JI, Jang IS, Park J.
Park R, et al. Among authors: jang m, jang is.
FASEB J. 2019 Dec;33(12):13216-13227. doi: 10.1096/fj.201900366R. Epub 2019 Sep 18.
FASEB J. 2019.
PMID: 31533005
Although p53 mutations are commonly found in many cancers, p53 is functionally inactivated in tumor cells that retain wild-type p53. ...These results collectively indicated that LNX1 contributed to tumor growth by inhibiting p53-dependent signaling in p53 wild-type cancer …
Although p53 mutations are commonly found in many cancers, p53 is functionally inactivated in tumor cells that retain wild-type p53. …