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Sm-p80-based schistosomiasis vaccine: double-blind preclinical trial in baboons demonstrates comprehensive prophylactic and parasite transmission-blocking efficacy.
Zhang W, Molehin AJ, Rojo JU, Sudduth J, Ganapathy PK, Kim E, Siddiqui AJ, Freeborn J, Sennoune SR, May J, Lazarus S, Nguyen C, Redman WK, Ahmad G, Torben W, Karmakar S, Le L, Kottapalli KR, Kottapalli P, Wolf RF, Papin JF, Carey D, Gray SA, Bergthold JD, Damian RT, Mayer BT, Marks F, Reed SG, Carter D, Siddiqui AA. Zhang W, et al. Among authors: wolf rf. Ann N Y Acad Sci. 2018 Aug;1425(1):38-51. doi: 10.1111/nyas.13942. Ann N Y Acad Sci. 2018. PMID: 30133707 Free PMC article.
Preclinical prophylactic efficacy testing of Sm-p80-based vaccine in a nonhuman primate model of Schistosoma mansoni infection and immunoglobulin G and E responses to Sm-p80 in human serum samples from an area where schistosomiasis is endemic.
Ahmad G, Zhang W, Torben W, Ahrorov A, Damian RT, Wolf RF, White GL, Carey DW, Mwinzi PN, Ganley-Leal L, Kennedy RC, Siddiqui AA. Ahmad G, et al. Among authors: wolf rf. J Infect Dis. 2011 Nov;204(9):1437-49. doi: 10.1093/infdis/jir545. Epub 2011 Sep 15. J Infect Dis. 2011. PMID: 21921206 Free PMC article.
Longevity of Sm-p80-specific antibody responses following vaccination with Sm-p80 vaccine in mice and baboons and transplacental transfer of Sm-p80-specific antibodies in a baboon.
Zhang W, Ahmad G, Le L, Rojo JU, Karmakar S, Tillery KA, Torben W, Damian RT, Wolf RF, White GL, Carey DW, Carter D, Reed SG, Siddiqui AA. Zhang W, et al. Among authors: wolf rf. Parasitol Res. 2014 Jun;113(6):2239-50. doi: 10.1007/s00436-014-3879-8. Epub 2014 Apr 12. Parasitol Res. 2014. PMID: 24728521 Free PMC article.
Fifteen Years of Sm-p80-Based Vaccine Trials in Nonhuman Primates: Antibodies From Vaccinated Baboons Confer Protection in vivo and in vitro From Schistosoma mansoni and Identification of Putative Correlative Markers of Protection.
Zhang W, Le L, Ahmad G, Molehin AJ, Siddiqui AJ, Torben W, Karmakar S, Rojo JU, Sennoune S, Lazarus S, Khatoon S, Freeborn J, Sudduth J, Rezk AF, Carey D, Wolf RF, Papin JF, Damian R, Gray SA, Marks F, Carter D, Siddiqui AA. Zhang W, et al. Among authors: wolf rf. Front Immunol. 2020 Jun 19;11:1246. doi: 10.3389/fimmu.2020.01246. eCollection 2020. Front Immunol. 2020. PMID: 32636844 Free PMC article.
143 results