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Sm-p80-based schistosomiasis vaccine: double-blind preclinical trial in baboons demonstrates comprehensive prophylactic and parasite transmission-blocking efficacy.
Zhang W, Molehin AJ, Rojo JU, Sudduth J, Ganapathy PK, Kim E, Siddiqui AJ, Freeborn J, Sennoune SR, May J, Lazarus S, Nguyen C, Redman WK, Ahmad G, Torben W, Karmakar S, Le L, Kottapalli KR, Kottapalli P, Wolf RF, Papin JF, Carey D, Gray SA, Bergthold JD, Damian RT, Mayer BT, Marks F, Reed SG, Carter D, Siddiqui AA. Zhang W, et al. Among authors: torben w. Ann N Y Acad Sci. 2018 Aug;1425(1):38-51. doi: 10.1111/nyas.13942. Ann N Y Acad Sci. 2018. PMID: 30133707 Free PMC article.
Prime-boost and recombinant protein vaccination strategies using Sm-p80 protects against Schistosoma mansoni infection in the mouse model to levels previously attainable only by the irradiated cercarial vaccine.
Ahmad G, Zhang W, Torben W, Haskins C, Diggs S, Noor Z, Le L, Siddiqui AA. Ahmad G, et al. Among authors: torben w. Parasitol Res. 2009 Nov;105(6):1767-77. doi: 10.1007/s00436-009-1646-z. Epub 2009 Oct 7. Parasitol Res. 2009. PMID: 19809833 Free PMC article.
Preclinical prophylactic efficacy testing of Sm-p80-based vaccine in a nonhuman primate model of Schistosoma mansoni infection and immunoglobulin G and E responses to Sm-p80 in human serum samples from an area where schistosomiasis is endemic.
Ahmad G, Zhang W, Torben W, Ahrorov A, Damian RT, Wolf RF, White GL, Carey DW, Mwinzi PN, Ganley-Leal L, Kennedy RC, Siddiqui AA. Ahmad G, et al. Among authors: torben w. J Infect Dis. 2011 Nov;204(9):1437-49. doi: 10.1093/infdis/jir545. Epub 2011 Sep 15. J Infect Dis. 2011. PMID: 21921206 Free PMC article.
36 results