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De novo NAD+ biosynthetic impairment in acute kidney injury in humans.
Poyan Mehr A, Tran MT, Ralto KM, Leaf DE, Washco V, Messmer J, Lerner A, Kher A, Kim SH, Khoury CC, Herzig SJ, Trovato ME, Simon-Tillaux N, Lynch MR, Thadhani RI, Clish CB, Khabbaz KR, Rhee EP, Waikar SS, Berg AH, Parikh SM. Poyan Mehr A, et al. Among authors: parikh sm. Nat Med. 2018 Sep;24(9):1351-1359. doi: 10.1038/s41591-018-0138-z. Epub 2018 Aug 20. Nat Med. 2018. PMID: 30127395 Free PMC article. Clinical Trial.
PGC-1α promotes recovery after acute kidney injury during systemic inflammation in mice.
Tran M, Tam D, Bardia A, Bhasin M, Rowe GC, Kher A, Zsengeller ZK, Akhavan-Sharif MR, Khankin EV, Saintgeniez M, David S, Burstein D, Karumanchi SA, Stillman IE, Arany Z, Parikh SM. Tran M, et al. Among authors: parikh sm. J Clin Invest. 2011 Oct;121(10):4003-14. doi: 10.1172/JCI58662. Epub 2011 Sep 1. J Clin Invest. 2011. PMID: 21881206 Free PMC article.
Mitochondrial biogenesis in the acutely injured kidney.
Tran M, Parikh SM. Tran M, et al. Among authors: parikh sm. Nephron Clin Pract. 2014;127(1-4):42-5. doi: 10.1159/000363715. Epub 2014 Sep 24. Nephron Clin Pract. 2014. PMID: 25343819 Free article. Review.
A branched-chain amino acid metabolite drives vascular fatty acid transport and causes insulin resistance.
Jang C, Oh SF, Wada S, Rowe GC, Liu L, Chan MC, Rhee J, Hoshino A, Kim B, Ibrahim A, Baca LG, Kim E, Ghosh CC, Parikh SM, Jiang A, Chu Q, Forman DE, Lecker SH, Krishnaiah S, Rabinowitz JD, Weljie AM, Baur JA, Kasper DL, Arany Z. Jang C, et al. Among authors: parikh sm. Nat Med. 2016 Apr;22(4):421-6. doi: 10.1038/nm.4057. Epub 2016 Mar 7. Nat Med. 2016. PMID: 26950361 Free PMC article.
PGC1α drives NAD biosynthesis linking oxidative metabolism to renal protection.
Tran MT, Zsengeller ZK, Berg AH, Khankin EV, Bhasin MK, Kim W, Clish CB, Stillman IE, Karumanchi SA, Rhee EP, Parikh SM. Tran MT, et al. Among authors: parikh sm. Nature. 2016 Mar 24;531(7595):528-32. doi: 10.1038/nature17184. Epub 2016 Mar 16. Nature. 2016. PMID: 26982719 Free PMC article.
Mitochondria in Acute Kidney Injury.
Ralto KM, Parikh SM. Ralto KM, et al. Among authors: parikh sm. Semin Nephrol. 2016 Jan;36(1):8-16. doi: 10.1016/j.semnephrol.2016.01.005. Semin Nephrol. 2016. PMID: 27085731 Free PMC article. Review.
129 results