Mandrup-Poulsen T - Search Results

1

Regulation of the β-cell inflammasome and contribution to stress-induced cellular dysfunction and apoptosis.

Ghiasi SM, Dahllöf MS, Osmai Y, Osmai M, Jakobsen KK, Aivazidis A, Tyrberg B, Perruzza L, Prause MCB, Christensen DP, Fog-Tonnesen M, Lundh M, Grassi F, Chatenoud L, Mandrup-Poulsen T. Ghiasi SM, et al. Mol Cell Endocrinol. 2018 Dec 15;478:106-114. doi: 10.1016/j.mce.2018.08.001. Epub 2018 Aug 16. Mol Cell Endocrinol. 2018. PMID: 30121202

2

Calcium has a permissive role in interleukin-1beta-induced c-jun N-terminal kinase activation in insulin-secreting cells.

Størling J, Zaitsev SV, Kapelioukh IL, Karlsen AE, Billestrup N, Berggren PO, Mandrup-Poulsen T. Størling J, et al. Endocrinology. 2005 Jul;146(7):3026-36. doi: 10.1210/en.2005-0036. Epub 2005 Apr 14. Endocrinology. 2005. PMID: 15831571

3

G protein-coupled receptor 39 deficiency is associated with pancreatic islet dysfunction.

Holst B, Egerod KL, Jin C, Petersen PS, Østergaard MV, Hald J, Sprinkel AM, Størling J, Mandrup-Poulsen T, Holst JJ, Thams P, Orskov C, Wierup N, Sundler F, Madsen OD, Schwartz TW. Holst B, et al. Endocrinology. 2009 Jun;150(6):2577-85. doi: 10.1210/en.2008-1250. Epub 2009 Feb 12. Endocrinology. 2009. PMID: 19213833 Free PMC article.

4

Inhibition of nuclear factor-kappaB or Bax prevents endoplasmic reticulum stress- but not nitric oxide-mediated apoptosis in INS-1E cells.

Tonnesen MF, Grunnet LG, Friberg J, Cardozo AK, Billestrup N, Eizirik DL, Størling J, Mandrup-Poulsen T. Tonnesen MF, et al. Endocrinology. 2009 Sep;150(9):4094-103. doi: 10.1210/en.2009-0029. Epub 2009 Jun 25. Endocrinology. 2009. PMID: 19556421

5

Suppressor of cytokine signalling-3 inhibits Tumor necrosis factor-alpha induced apoptosis and signalling in beta cells.

Bruun C, Heding PE, Rønn SG, Frobøse H, Rhodes CJ, Mandrup-Poulsen T, Billestrup N. Bruun C, et al. Mol Cell Endocrinol. 2009 Nov 13;311(1-2):32-8. doi: 10.1016/j.mce.2009.07.019. Epub 2009 Jul 28. Mol Cell Endocrinol. 2009. PMID: 19643162

6

Direct demonstration of NCAM cis-dimerization and inhibitory effect of palmitoylation using the BRET2 technique.

Kulahin N, Grunnet LG, Lundh M, Christensen DP, Jorgensen R, Heding A, Billestrup N, Berezin V, Bock E, Mandrup-Poulsen T. Kulahin N, et al. FEBS Lett. 2011 Jan 3;585(1):58-64. doi: 10.1016/j.febslet.2010.11.043. Epub 2010 Nov 26. FEBS Lett. 2011. PMID: 21115007 Free article.

7

Histone deacetylase (HDAC) inhibition as a novel treatment for diabetes mellitus.

Christensen DP, Dahllöf M, Lundh M, Rasmussen DN, Nielsen MD, Billestrup N, Grunnet LG, Mandrup-Poulsen T. Christensen DP, et al. Mol Med. 2011 May-Jun;17(5-6):378-90. doi: 10.2119/molmed.2011.00021. Epub 2011 Jan 25. Mol Med. 2011. PMID: 21274504 Free PMC article. Review.

8

Apolipoprotein CIII reduces proinflammatory cytokine-induced apoptosis in rat pancreatic islets via the Akt prosurvival pathway.

Størling J, Juntti-Berggren L, Olivecrona G, Prause MC, Berggren PO, Mandrup-Poulsen T. Størling J, et al. Endocrinology. 2011 Aug;152(8):3040-8. doi: 10.1210/en.2010-1422. Epub 2011 Jun 21. Endocrinology. 2011. PMID: 21693679

9

Transcriptional and translational regulation of cytokine signaling in inflammatory β-cell dysfunction and apoptosis.

Novotny GW, Lundh M, Backe MB, Christensen DP, Hansen JB, Dahllöf MS, Pallesen EM, Mandrup-Poulsen T. Novotny GW, et al. Arch Biochem Biophys. 2012 Dec 15;528(2):171-84. doi: 10.1016/j.abb.2012.09.014. Epub 2012 Oct 9. Arch Biochem Biophys. 2012. PMID: 23063755 Review.

10

The lysine deacetylase inhibitor Givinostat inhibits β-cell IL-1β induced IL-1β transcription and processing.

Dahllöf MS, Christensen DP, Lundh M, Dinarello CA, Mascagni P, Grunnet LG, Mandrup-Poulsen T. Dahllöf MS, et al. Islets. 2012 Nov-Dec;4(6):417-22. doi: 10.4161/isl.23541. Islets. 2012. PMID: 23486342 Free PMC article.

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