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Linaclotide improves gastrointestinal transit in cystic fibrosis mice by inhibiting sodium/hydrogen exchanger 3.
Am J Physiol Gastrointest Liver Physiol. 2018 Nov 1;315(5):G868-G878. doi: 10.1152/ajpgi.00261.2017. Epub 2018 Aug 17.
Am J Physiol Gastrointest Liver Physiol. 2018.
PMID: 30118317
Free PMC article.
A G542X cystic fibrosis mouse model for examining nonsense mutation directed therapies.
McHugh DR, Steele MS, Valerio DM, Miron A, Mann RJ, LePage DF, Conlon RA, Cotton CU, Drumm ML, Hodges CA.
McHugh DR, et al.
PLoS One. 2018 Jun 20;13(6):e0199573. doi: 10.1371/journal.pone.0199573. eCollection 2018.
PLoS One. 2018.
PMID: 29924856
Free PMC article.
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A BAC Transgene Expressing Human CFTR under Control of Its Regulatory Elements Rescues Cftr Knockout Mice.
Gawenis LR, Hodges CA, McHugh DR, Valerio DM, Miron A, Cotton CU, Liu J, Walker NM, Strubberg AM, Gillen AE, Mutolo MJ, Kotzamanis G, Bosch J, Harris A, Drumm ML, Clarke LL.
Gawenis LR, et al. Among authors: mchugh dr.
Sci Rep. 2019 Aug 14;9(1):11828. doi: 10.1038/s41598-019-48105-4.
Sci Rep. 2019.
PMID: 31413336
Free PMC article.
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Synergy between Readthrough and Nonsense Mediated Decay Inhibition in a Murine Model of Cystic Fibrosis Nonsense Mutations.
McHugh DR, Cotton CU, Hodges CA.
McHugh DR, et al.
Int J Mol Sci. 2020 Dec 31;22(1):344. doi: 10.3390/ijms22010344.
Int J Mol Sci. 2020.
PMID: 33396210
Free PMC article.
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Steric interference from intrinsically disordered regions controls dynamin-related protein 1 self-assembly during mitochondrial fission.
Lu B, Kennedy B, Clinton RW, Wang EJ, McHugh D, Stepanyants N, Macdonald PJ, Mears JA, Qi X, Ramachandran R.
Lu B, et al.
Sci Rep. 2018 Jul 18;8(1):10879. doi: 10.1038/s41598-018-29001-9.
Sci Rep. 2018.
PMID: 30022112
Free PMC article.
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DAF-16 and SMK-1 Contribute to Innate Immunity During Adulthood in Caenorhabditis elegans.
McHugh DR, Koumis E, Jacob P, Goldfarb J, Schlaubitz-Garcia M, Bennani S, Regan P, Patel P, Youngman MJ.
McHugh DR, et al.
G3 (Bethesda). 2020 May 4;10(5):1521-1539. doi: 10.1534/g3.120.401166.
G3 (Bethesda). 2020.
PMID: 32161087
Free PMC article.
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Syphilis: an old disease with modern health concerns.
McHugh DR.
McHugh DR.
Nurse Pract Forum. 1996 Mar;7(1):34-9.
Nurse Pract Forum. 1996.
PMID: 8788662
Review.
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