Hansen LH - Search Results

1

Studies of Impending Oligonucleotide Therapeutics in Simulated Biofluids.

Domljanovic I, Hansen AH, Hansen LH, Klitgaard JK, Taskova M, Astakhova K. Domljanovic I, et al. Among authors: hansen ah, hansen lh. Nucleic Acid Ther. 2018 Dec;28(6):348-356. doi: 10.1089/nat.2017.0704. Epub 2018 Aug 14. Nucleic Acid Ther. 2018. PMID: 30106665

2

Antisense Oligonucleotides Internally Labeled with Peptides Show Improved Target Recognition and Stability to Enzymatic Degradation.

Taskova M, Madsen CS, Jensen KJ, Hansen LH, Vester B, Astakhova K. Taskova M, et al. Among authors: hansen lh. Bioconjug Chem. 2017 Mar 15;28(3):768-774. doi: 10.1021/acs.bioconjchem.6b00567. Epub 2016 Dec 1. Bioconjug Chem. 2017. PMID: 28292178

3

Peptide-LNA oligonucleotide conjugates.

Astakhova IK, Hansen LH, Vester B, Wengel J. Astakhova IK, et al. Among authors: hansen lh. Org Biomol Chem. 2013 Jul 7;11(25):4240-9. doi: 10.1039/c3ob40786a. Org Biomol Chem. 2013. PMID: 23681061 Free article.

4

Amplification and re-generation of LNA-modified libraries.

Doessing H, Hansen LH, Veedu RN, Wengel J, Vester B. Doessing H, et al. Among authors: hansen lh. Molecules. 2012 Nov 5;17(11):13087-97. doi: 10.3390/molecules171113087. Molecules. 2012. PMID: 23128088 Free PMC article.

5

Easily denaturing nucleic acids derived from intercalating nucleic acids: thermal stability studies, dual duplex invasion and inhibition of transcription start.

Filichev VV, Vester B, Hansen LH, Pedersen EB. Filichev VV, et al. Among authors: hansen lh. Nucleic Acids Res. 2005 Dec 23;33(22):7129-37. doi: 10.1093/nar/gki1019. Print 2005. Nucleic Acids Res. 2005. PMID: 16377781 Free PMC article.

6

Locked nucleoside analogues expand the potential of DNAzymes to cleave structured RNA targets.

Vester B, Hansen LH, Lundberg LB, Babu BR, Sørensen MD, Wengel J, Douthwaite S. Vester B, et al. Among authors: hansen lh. BMC Mol Biol. 2006 Jun 5;7:19. doi: 10.1186/1471-2199-7-19. BMC Mol Biol. 2006. PMID: 16753066 Free PMC article.

7

Enhanced inhibition of transcription start by targeting with 2'-OMe pentaribonucleotides comprising locked nucleic acids and intercalating nucleic acids.

Filichev VV, Vester B, Hansen LH, Abdel Aal MT, Babu BR, Wengel J, Pedersen EB. Filichev VV, et al. Among authors: hansen lh. Chembiochem. 2005 Jul;6(7):1181-4. doi: 10.1002/cbic.200400457. Chembiochem. 2005. PMID: 15912554 No abstract available.

8

Minimal substrate features for Erm methyltransferases defined by using a combinatorial oligonucleotide library.

Hansen LH, Lobedanz S, Douthwaite S, Arar K, Wengel J, Kirpekar F, Vester B. Hansen LH, et al. Chembiochem. 2011 Mar 7;12(4):610-4. doi: 10.1002/cbic.201000606. Epub 2011 Jan 24. Chembiochem. 2011. PMID: 21264994

9

Selection of G-quadruplex folding topology with LNA-modified human telomeric sequences in K+ solution.

Pradhan D, Hansen LH, Vester B, Petersen M. Pradhan D, et al. Among authors: hansen lh. Chemistry. 2011 Feb 18;17(8):2405-13. doi: 10.1002/chem.201001961. Epub 2011 Jan 24. Chemistry. 2011. PMID: 21264960

10

Improvement of a streptavidin-binding aptamer by LNA- and α-l-LNA-substitutions.

Jørgensen AS, Hansen LH, Vester B, Wengel J. Jørgensen AS, et al. Among authors: hansen lh. Bioorg Med Chem Lett. 2014 May 15;24(10):2273-7. doi: 10.1016/j.bmcl.2014.03.082. Epub 2014 Apr 3. Bioorg Med Chem Lett. 2014. PMID: 24745966

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