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A Noncanonical Metal Center Drives the Activity of the Sediminispirochaeta smaragdinae Metallo-β-lactamase SPS-1.
Cheng Z, VanPelt J, Bergstrom A, Bethel C, Katko A, Miller C, Mason K, Cumming E, Zhang H, Kimble RL, Fullington S, Bretz SL, Nix JC, Bonomo RA, Tierney DL, Page RC, Crowder MW. Cheng Z, et al. Among authors: vanpelt j. Biochemistry. 2018 Sep 4;57(35):5218-5229. doi: 10.1021/acs.biochem.8b00728. Epub 2018 Aug 21. Biochemistry. 2018. PMID: 30106565 Free PMC article.
Clinical Variants of New Delhi Metallo-β-Lactamase Are Evolving To Overcome Zinc Scarcity.
Stewart AC, Bethel CR, VanPelt J, Bergstrom A, Cheng Z, Miller CG, Williams C, Poth R, Morris M, Lahey O, Nix JC, Tierney DL, Page RC, Crowder MW, Bonomo RA, Fast W. Stewart AC, et al. Among authors: vanpelt j. ACS Infect Dis. 2017 Dec 8;3(12):927-940. doi: 10.1021/acsinfecdis.7b00128. Epub 2017 Oct 11. ACS Infect Dis. 2017. PMID: 28965402 Free PMC article.
Evolution of New Delhi metallo-β-lactamase (NDM) in the clinic: Effects of NDM mutations on stability, zinc affinity, and mono-zinc activity.
Cheng Z, Thomas PW, Ju L, Bergstrom A, Mason K, Clayton D, Miller C, Bethel CR, VanPelt J, Tierney DL, Page RC, Bonomo RA, Fast W, Crowder MW. Cheng Z, et al. Among authors: vanpelt j. J Biol Chem. 2018 Aug 10;293(32):12606-12618. doi: 10.1074/jbc.RA118.003835. Epub 2018 Jun 16. J Biol Chem. 2018. PMID: 29909397 Free PMC article.
Different Conformations Revealed by NMR Underlie Resistance to Ceftazidime/Avibactam and Susceptibility to Meropenem and Imipenem among D179Y Variants of KPC β-Lactamase.
Taracila MA, Bethel CR, Hujer AM, Papp-Wallace KM, Barnes MD, Rutter JD, VanPelt J, Shurina BA, van den Akker F, Clancy CJ, Nguyen MH, Cheng S, Shields RK, Page RC, Bonomo RA. Taracila MA, et al. Among authors: vanpelt j. Antimicrob Agents Chemother. 2022 Apr 19;66(4):e0212421. doi: 10.1128/aac.02124-21. Epub 2022 Mar 21. Antimicrob Agents Chemother. 2022. PMID: 35311523 Free PMC article.
Mapping protein-polymer conformations in bioconjugates with atomic precision.
Burridge KM, Shurina BA, Kozuszek CT, Parnell RF, Montgomery JS, VanPelt JL, Daman NM, McCarrick RM, Ramelot TA, Konkolewicz D, Page RC. Burridge KM, et al. Among authors: vanpelt jl. Chem Sci. 2020 Jun 3;11(24):6160-6166. doi: 10.1039/d0sc02200d. eCollection 2020 Jun 28. Chem Sci. 2020. PMID: 32953011 Free PMC article.
[No title available]
[No authors listed] [No authors listed] PMID: 33453896
16 results