Minter R - Search Results

1

TNFR2 ligation in human T regulatory cells enhances IL2-induced cell proliferation through the non-canonical NF-κB pathway.

Wang J, Ferreira R, Lu W, Farrow S, Downes K, Jermutus L, Minter R, Al-Lamki RS, Pober JS, Bradley JR. Wang J, et al. Among authors: minter r. Sci Rep. 2018 Aug 13;8(1):12079. doi: 10.1038/s41598-018-30621-4. Sci Rep. 2018. PMID: 30104686 Free PMC article.

2

Phenotypic screening reveals TNFR2 as a promising target for cancer immunotherapy.

Williams GS, Mistry B, Guillard S, Ulrichsen JC, Sandercock AM, Wang J, González-Muñoz A, Parmentier J, Black C, Soden J, Freeth J, Jovanović J, Leyland R, Al-Lamki RS, Leishman AJ, Rust SJ, Stewart R, Jermutus L, Bradley JR, Bedian V, Valge-Archer V, Minter R, Wilkinson RW. Williams GS, et al. Among authors: minter r. Oncotarget. 2016 Oct 18;7(42):68278-68291. doi: 10.18632/oncotarget.11943. Oncotarget. 2016. PMID: 27626702 Free PMC article.

3

Harnessing phage and ribosome display for antibody optimisation.

Dufner P, Jermutus L, Minter RR. Dufner P, et al. Among authors: minter rr. Trends Biotechnol. 2006 Nov;24(11):523-9. doi: 10.1016/j.tibtech.2006.09.004. Epub 2006 Sep 26. Trends Biotechnol. 2006. PMID: 17000017 Review.

4

A series of Fas receptor agonist antibodies that demonstrate an inverse correlation between affinity and potency.

Chodorge M, Züger S, Stirnimann C, Briand C, Jermutus L, Grütter MG, Minter RR. Chodorge M, et al. Among authors: minter rr. Cell Death Differ. 2012 Jul;19(7):1187-95. doi: 10.1038/cdd.2011.208. Epub 2012 Jan 20. Cell Death Differ. 2012. PMID: 22261618 Free PMC article.

5

In vitro DNA recombination by L-Shuffling during ribosome display affinity maturation of an anti-Fas antibody increases the population of improved variants.

Chodorge M, Fourage L, Ravot G, Jermutus L, Minter R. Chodorge M, et al. Among authors: minter r. Protein Eng Des Sel. 2008 May;21(5):343-51. doi: 10.1093/protein/gzn013. Protein Eng Des Sel. 2008. PMID: 18411227

6

Tailored amino acid diversity for the evolution of antibody affinity.

González-Muñoz A, Bokma E, O'Shea D, Minton K, Strain M, Vousden K, Rossant C, Jermutus L, Minter R. González-Muñoz A, et al. Among authors: minter r. MAbs. 2012 Nov-Dec;4(6):664-72. doi: 10.4161/mabs.21728. Epub 2012 Aug 27. MAbs. 2012. PMID: 22926024 Free PMC article.

7

Improved drug-like properties of therapeutic proteins by directed evolution.

Buchanan A, Ferraro F, Rust S, Sridharan S, Franks R, Dean G, McCourt M, Jermutus L, Minter R. Buchanan A, et al. Among authors: minter r. Protein Eng Des Sel. 2012 Oct;25(10):631-8. doi: 10.1093/protein/gzs054. Epub 2012 Aug 31. Protein Eng Des Sel. 2012. PMID: 22942395 Free PMC article.

8

Engineering a therapeutic IgG molecule to address cysteinylation, aggregation and enhance thermal stability and expression.

Buchanan A, Clementel V, Woods R, Harn N, Bowen MA, Mo W, Popovic B, Bishop SM, Dall'Acqua W, Minter R, Jermutus L, Bedian V. Buchanan A, et al. Among authors: minter r. MAbs. 2013 Mar-Apr;5(2):255-62. doi: 10.4161/mabs.23392. Epub 2013 Feb 14. MAbs. 2013. PMID: 23412563 Free PMC article.

9

Combining phenotypic and proteomic approaches to identify membrane targets in a 'triple negative' breast cancer cell type.

Rust S, Guillard S, Sachsenmeier K, Hay C, Davidson M, Karlsson A, Karlsson R, Brand E, Lowne D, Elvin J, Flynn M, Kurosawa G, Hollingsworth R, Jermutus L, Minter R. Rust S, et al. Among authors: minter r. Mol Cancer. 2013 Feb 13;12:11. doi: 10.1186/1476-4598-12-11. Mol Cancer. 2013. PMID: 23406016 Free PMC article.

10

Combinatorial Screening Identifies Novel Promiscuous Matrix Metalloproteinase Activities that Lead to Inhibition of the Therapeutic Target IL-13.

Urbach C, Gordon NC, Strickland I, Lowne D, Joberty-Candotti C, May R, Herath A, Hijnen D, Thijs JL, Bruijnzeel-Koomen CA, Minter RR, Hollfelder F, Jermutus L. Urbach C, et al. Among authors: minter rr. Chem Biol. 2015 Nov 19;22(11):1442-1452. doi: 10.1016/j.chembiol.2015.09.013. Epub 2015 Nov 5. Chem Biol. 2015. PMID: 26548614

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