Lee J - Search Results

1

Pyrazinyl ureas revisited: 1-(3-(Benzyloxy)pyrazin-2-yl)-3-(3,4-dichlorophenyl)urea, a new blocker of Aβ-induced mPTP opening for Alzheimer's disease.

Elkamhawy A, Park JE, Hassan AHE, Pae AN, Lee J, Paik S, Park BG, Roh EJ. Elkamhawy A, et al. Among authors: lee j. Eur J Med Chem. 2018 Sep 5;157:268-278. doi: 10.1016/j.ejmech.2018.07.068. Epub 2018 Jul 31. Eur J Med Chem. 2018. PMID: 30098482

2

N-(3-acyloxy-2-benzylpropyl)-N'-[4-(methylsulfonylamino)benzyl]thiourea analogues: novel potent and high affinity antagonists and partial antagonists of the vanilloid receptor.

Lee J, Lee J, Kang M, Shin M, Kim JM, Kang SU, Lim JO, Choi HK, Suh YG, Park HG, Oh U, Kim HD, Park YH, Ha HJ, Kim YH, Toth A, Wang Y, Tran R, Pearce LV, Lundberg DJ, Blumberg PM. Lee J, et al. J Med Chem. 2003 Jul 3;46(14):3116-26. doi: 10.1021/jm030089u. J Med Chem. 2003. PMID: 12825950

3

The SAR analysis of TRPV1 agonists with the α-methylated B-region.

Cho Y, Kim MS, Kim HS, Ann J, Lee J, Pearce LV, Pavlyukovets VA, Morgan MA, Blumberg PM, Lee J. Cho Y, et al. Among authors: lee j. Bioorg Med Chem Lett. 2012 Aug 15;22(16):5227-31. doi: 10.1016/j.bmcl.2012.06.059. Epub 2012 Jun 23. Bioorg Med Chem Lett. 2012. PMID: 22796184 Free PMC article.

4

Synthesis and evaluation of oxime derivatives as modulators for amyloid beta-induced mitochondrial dysfunction.

Kim YS, Jung SH, Park BG, Ko MK, Jang HS, Choi K, Baik JH, Lee J, Lee JK, Pae AN, Cho YS, Min SJ. Kim YS, et al. Among authors: lee j, lee jk. Eur J Med Chem. 2013 Apr;62:71-83. doi: 10.1016/j.ejmech.2012.12.033. Epub 2012 Dec 26. Eur J Med Chem. 2013. PMID: 23353734

5

Novel pyrimidoazepine analogs as serotonin 5-HT(2A) and 5-HT(2C) receptor ligands for the treatment of obesity.

Yang HY, Tae J, Seo YW, Kim YJ, Im HY, Choi GD, Cho H, Park WK, Kwon OS, Cho YS, Ko M, Jang H, Lee J, Choi K, Kim CH, Lee J, Pae AN. Yang HY, et al. Among authors: lee j. Eur J Med Chem. 2013 May;63:558-69. doi: 10.1016/j.ejmech.2013.02.020. Epub 2013 Feb 27. Eur J Med Chem. 2013. PMID: 23537943

6

Structure-activity relationship of human glutaminyl cyclase inhibitors having an N-(5-methyl-1H-imidazol-1-yl)propyl thiourea template.

Tran PT, Hoang VH, Thorat SA, Kim SE, Ann J, Chang YJ, Nam DW, Song H, Mook-Jung I, Lee J, Lee J. Tran PT, et al. Among authors: lee j. Bioorg Med Chem. 2013 Jul 1;21(13):3821-30. doi: 10.1016/j.bmc.2013.04.005. Epub 2013 Apr 17. Bioorg Med Chem. 2013. PMID: 23643900

7

Aminopropyl carbazole analogues as potent enhancers of neurogenesis.

Yoon HJ, Kong SY, Park MH, Cho Y, Kim SE, Shin JY, Jung S, Lee J, Farhanullah, Kim HJ, Lee J. Yoon HJ, et al. Among authors: lee j. Bioorg Med Chem. 2013 Nov 15;21(22):7165-74. doi: 10.1016/j.bmc.2013.08.066. Epub 2013 Sep 8. Bioorg Med Chem. 2013. PMID: 24095011

8

Synthesis and biological evaluation of aryloxazole derivatives as antimitotic and vascular-disrupting agents for cancer therapy.

Choi MJ, No ES, Thorat DA, Jang JW, Yang H, Lee J, Choo H, Kim SJ, Lee CS, Ko SY, Lee J, Nam G, Pae AN. Choi MJ, et al. Among authors: lee j, lee cs. J Med Chem. 2013 Nov 27;56(22):9008-18. doi: 10.1021/jm400840p. Epub 2013 Nov 14. J Med Chem. 2013. PMID: 24160376

9

Novel quinazoline-urea analogues as modulators for Aβ-induced mitochondrial dysfunction: design, synthesis, and molecular docking study.

Elkamhawy A, Lee J, Park BG, Park I, Pae AN, Roh EJ. Elkamhawy A, et al. Among authors: lee j. Eur J Med Chem. 2014 Sep 12;84:466-75. doi: 10.1016/j.ejmech.2014.07.027. Epub 2014 Jul 9. Eur J Med Chem. 2014. PMID: 25050879

10

Synthesis and biological evaluation of aryl isoxazole derivatives as metabotropic glutamate receptor 1 antagonists: a potential treatment for neuropathic pain.

Cho GH, Kim T, Son WS, Seo SH, Min SJ, Cho YS, Keum G, Jeong KS, Koh HY, Lee J, Pae AN. Cho GH, et al. Among authors: lee j. Bioorg Med Chem Lett. 2015 Mar 15;25(6):1324-8. doi: 10.1016/j.bmcl.2015.01.035. Epub 2015 Jan 24. Bioorg Med Chem Lett. 2015. PMID: 25677662

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