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TSSC3 promotes autophagy via inactivating the Src-mediated PI3K/Akt/mTOR pathway to suppress tumorigenesis and metastasis in osteosarcoma, and predicts a favorable prognosis.
Zhao GS, Gao ZR, Zhang Q, Tang XF, Lv YF, Zhang ZS, Zhang Y, Tan QL, Peng DB, Jiang DM, Guo QN. Zhao GS, et al. Among authors: zhang q, zhang zs, zhang y. J Exp Clin Cancer Res. 2018 Aug 9;37(1):188. doi: 10.1186/s13046-018-0856-6. J Exp Clin Cancer Res. 2018. PMID: 30092789 Free PMC article.
High expression of ID1 facilitates metastasis in human osteosarcoma by regulating the sensitivity of anoikis via PI3K/AKT depended suppression of the intrinsic apoptotic signaling pathway.
Zhao GS, Zhang Q, Cao Y, Wang Y, Lv YF, Zhang ZS, Zhang Y, Tan QL, Chang Y, Quan ZX, Jiang DM, Guo QN. Zhao GS, et al. Among authors: zhang q, zhang zs, zhang y. Am J Transl Res. 2019 Apr 15;11(4):2117-2139. eCollection 2019. Am J Transl Res. 2019. PMID: 31105823 Free PMC article.
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